Andre browsed the order page curiously.

This is a separate ordering website, the name of the website is ene, and it is operated as a global non-profit organization.

There is an item 'How to order' at the top, and after clicking it, the 'Order Instructions' will appear.

The entire page is simple and beautiful, looks very professional, and the ordering process is also very clear.

Any researcher anywhere in the world, as long as they have a computer or mobile phone, can order the samples they need with a few simple clicks.

In the next few days, the product will be delivered to your door, and the researchers only need to combine it with the guide RNA of the gene they want to cut off.

Even this last step can be ordered through the website.

The whole process is similar to shopping online on Amazon.com.

Andre immediately clicked the mouse and tried to place an order.

In principle, orders can only be completed online, and orders by phone or other methods cannot be accepted, so personal information must be filled in first to register.

Andre clicked 'Register'. The first step was to select a country. After selecting the Eagle Country, he entered the second step, 'Select Unit'. There were three options, research institution/non-profit organization, enterprise, or individual.

Out of curiosity, he tried to select the 'research institution' option, and a row of names of Yingguo universities popped up instantly. When he scrolled down, he suddenly saw the school where he graduated.

Select the name of the school you graduated from and click OK. A list of college names of the selected university will pop up.

After choosing a college, the names of professors and associate professors working in that college will be further listed.

Andre browsed through it, found the name of his instructor, and clicked to confirm.

Immediately enter the last step, you can enter your name, email and contact number to complete the registration.

The whole process was very smooth, and the most important thing is that the names of so many university teachers can be listed.

He couldn't help but secretly marvel, and returned to the second step, choosing the option of 'Enterprise'.

What jumped out this time were the names of Pfizer, Johnson & Johnson, Eli Lilly, AbbVie, Biogen, Genentech, etc., Eagle Country Pharmaceuticals and biotechnology companies.

Andre chose Pfizer without hesitation, and a list of names of researchers appeared in front of him.

He is very familiar with these names, most of them are his colleagues, and some of them are subordinates of his oncology department.

As expected, he also saw his own name, and after clicking on it, he went directly to the last step.

After the account is successfully registered, you can enter the order page.

You can choose the version of the original bacterium protein you need, or customize the required guide RNA.

The former is free, but you need to pay postage, while the latter requires you to pay a certain amount depending on your needs, but the price is not expensive, probably within a hundred dollars.

In terms of quantity, there are certain restrictions. Often an order is limited to 10 for individuals and 50 for institutions and businesses.

In this way, the website limits orders to academic research and only offers a limited number of free samples at a time.

If you want to use it for large-scale commercial applications, you can only purchase it from Sanqing through formal channels.

If you have any questions during the ordering process, you can provide consultation services through the email and phone numbers provided on the website.

Next, click the ‘Add to Cart’ button just like you’re actually shopping on Amazon.

Then fill in a valid delivery address, pay and settle, and the order is completed. The whole process is very convenient and fast.

Thanks to the highly developed transportation and delivery system in today's society, after receiving the order, the samples packed into small test tubes will be put into cartons at a certain time of the day and sent to all parts of the world.

These cartons are managed through barcodes, so that researchers in the world who purchased the samples can all be traced.

The business is booming, and the website receives an average of hundreds of orders from all over the world every day, and then delivers samples to 38 countries and regions around the world.

The entire website is equivalent to a "trial" system, promoting easy-to-use gene editing tools to the world in the form of free gifts.

This way, any researcher can simply purchase and obtain the samples they need.

Andre went to the last step and successfully placed an order in the name of the company.

After he gets the sample, he plans to let the laboratory try it out to see what the actual effect is.

At the same time, we also need to compare it with the Crispr-Cas 9 technology of the Broad Institute to see which one is better.

Although there were rumors everywhere that Sanqing's new technology was so awesome that it beat everything else, he still had some doubts in his heart.

I wonder if this new technology is really as good as rumored?

Only seeing is believing can he be completely convinced.

****

A few days later, Andre received the sample at the company.

Then he rushed to the rare disease division and found the person in charge of the laboratory.

"Dr. Duke, good news, I brought you a gift. I believe you will like it."

Andre handed over the cardboard box in his hand.

Dr. Duke has gray hair and is over sixty years old, but he is still energetic and has bright eyes.

He took it with a puzzled look on his face, and when he saw the letters "sanqing" on it, his expression suddenly changed.

I immediately opened the carton and saw a neat row of glass test tubes inside.

I casually picked up a glass test tube and saw the English label on it. My eyes suddenly lit up and I was filled with surprise.

"Wow, Andre, your gift won't be Sanqing's arc1 protein sample, right? This is a huge surprise!"

Dr. Duke immediately danced with joy and took Andre straight to the laboratory, introducing it endlessly as he walked.

"We are currently conducting research on gene therapy for hemophilia, and we have some promising results, but there is still a certain distance before clinical trials."

"Our researchers isolated epithelial cells on the surface of the urinary tract from the urine of seven patients with severe hemophilia A and reprogrammed them into induced pluripotent stem cells (ips cells). Then they gene edited the ips cells,

Multiple copies of the normal gene for factor viii were inserted."

"After these endothelial cells were implanted into the subcutaneous tissue of hemophilia A mice, they formed a vascular network. The blood vessels directly transported functional factor viii directly into the blood, and the secreted protein was sufficient to supply the whole body."

"The results are very encouraging. After endothelial cells were implanted in the mice, circulating coagulation factor viii increased by 600% and normal coagulation was restored."

"Currently, this therapy can only be implemented in mouse models of hemophilia A. As for experiments in human cells, due to the complicated steps, when using CRISPR-Cas 9 technology for gene editing, the off-target rate is high.

, the success rate is not very satisfactory.”

"But since you brought these treasures," Dr. Duke smiled and raised the test tube in his hand, his eyes full of expectation.

"We hope that Sanqing's new genetic technology can bring us new breakthroughs."

****

Two weeks later, Dr. Duke looked at the experimental results in front of him, dumbfounded and in disbelief.

"Oh my god! Miracle! This must be a miracle!"

There were bursts of exclamations and screams behind him.

The researchers in the laboratory stared at the screen, each one in a state of despair, as if they had seen a ghost.

Dr. Duke was well-informed and reacted quickly, coughing slightly to wake everyone up from their gaffe.

"I really can't believe that after so many years of hard research, there was a qualitative breakthrough in just two weeks."

A senior researcher murmured, with a complicated expression on his face, joy and annoyance appearing at the same time, intertwined.

"If only Sanqing's genetic technology could be used earlier, our genetic drugs for hemophilia would have been on the market long ago, and patients would have been saved sooner."

Another researcher's eyes were sad, he lowered his head and sighed, as if he recalled some not-so-pleasant memories.

Dr. Duke burst out with hearty laughter and encouraged everyone: "It's not too late, haha."

"Today is a wonderful day. Our gene drug for hemophilia has finally made clinical progress, and we deserve to celebrate."

The whole place burst into cheers instantly, and people smiled one after another, delighted with the results achieved.

Dr. Duke arranged the follow-up work, took the experimental results, and turned around and left.

This exciting result must be reported to the company's senior management immediately, and clinical trials must be promoted as soon as possible to strive for an early launch.

He can already imagine that after Sanqing's fourth-generation gene technology is released, Pfizer will not be the only one to use it to achieve breakthroughs.

Bayer, Novartis, Bogen, Roche, these greedy and ambitious colleagues must also be in the laboratory, working day and night with red eyes, trying their best to break through the difficulties of genetic drugs.

With the blessing of new technologies, the time for them to achieve breakthroughs will only become faster and faster, and competition will become increasingly fierce.

Pfizer, as the number one pharmaceutical company in the world, must not lose at the starting line, let alone fall behind its opponents.

****

Yingguo Xincun City, Pfizer headquarters building.

In the spacious and bright office, it was noisy at the moment, as noisy as a vegetable market.

Company executives and directors of major laboratories gathered together, talking and whispering.

Pfizer CEO Albert looked around and patted the table gently: "Gentlemen, be quiet!"

When everyone calmed down, he looked at Dr. Duke with a serious face.

"Today, I want to tell you some good news. The laboratory has successfully developed a genetic drug for hemophilia. The specific situation will be described by Dr. Duke."
To be continued...