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Chapter 477 The Disruptor of the Artificial Organ Market(1/2)

In the next few days, projects such as chronic nephritis drugs, antioxidant drugs, asthma drugs, hypoglycemic drugs, anti-inflammatory drugs, ultrasound blood vessels, bionic painless syringes, artificial blood vessels, and artificial hearts were all launched.

It's okay to say that those five drugs are not eye-catching among the dozens of drugs under development in Sanqing's entire pipeline. They just need to steadily advance clinical trials.

But the three medical device products that were thrown out at once, including high-tech projects such as artificial hearts and artificial blood vessels, surprised Lu Tingfeng.

"Mr. Wei, these three projects look very high-end. I'm afraid they won't be able to see results in the short term."

Lu Tingfeng looked at the information in front of him, his face was shocked, and he was speechless.

"Artificial blood vessels, artificial hearts, these are the most cutting-edge technologies, and you can do them. It's really amazing."

"Haha, it's not all my fault, I just made a slight improvement on it."

"The main credit goes to the Pangu Research Institute. There are many talented scientific researchers there, and they also cooperate with many scientific research institutions. They often produce some good technical results."

Wei Kang pointed it out and said with a smile: "Anyway, let's start the project first. It's one thing to be able to do it in the laboratory, it's another thing to be able to produce it industrially. It's up to you whether you can make back all the money you invested.

That’s it.”

"I understand, don't worry, I'll take care of it." Lu Tingfeng agreed without thinking too much.

After all, life is priceless, and it really has to be measured by money, so it will never be too low.

In the absence of small-diameter artificial blood vessels, patients can only use their own blood vessels for transplantation, which has very limited sources and can cause huge trauma to the human body.

The artificial heart itself is also very small, with a thickness of 2 cm, a diameter of 3 cm, and a weight of only 90 grams. It is very light and will not add much extra burden to the patient.

Lu Tingfeng couldn't help but think deeply: "It is true. I am very optimistic about this product. More importantly, we can extend this bionic idea to the research and development of medical devices."

"Yes, nature's creations are actually very smart and have different exquisite structures, so we humans need to learn more about nature's clever designs from them." Wei Kang couldn't help but laugh.

"The whole process combines vibration and penetration, and it is as smooth as a hammer drill penetrating butter. It can reach the capillaries without much effort."

However, high-end equipment such as an artificial heart can only be used on one patient and can extend the patient's life for more than ten years. Its value is infinite and immeasurable.

"Even a domestically produced artificial heart costs 600,000 yuan, and a major heart surgery like this costs 200,000 yuan."

As for the next generation of artificial hearts that are being vigorously developed by various countries, they basically cannot escape this model. They only have some improvements in weight, allowing patients to bear less daily weight.

There have been studies on this at home and abroad for a long time, and they have focused on biological protein materials such as silk, but no usable products have been available.

When he left, he looked excited and his whole person fell into an excited mood.

"What's even more frightening is that the mosquito's sting force is very slight, only 16.5 micronewtons."

One reason why we have to carry so many things is that the power of the artificial heart is too high, reaching an average of about 20W.

If the price is too high, it will not have much effect, and most people will still choose organ transplantation and wait for matching.

"Bionics is really amazing. It can actually imitate the mouthparts of mosquitoes and create similar micro-needles."

"The price of artificial hearts is quite high. Currently, an imported artificial heart equipment costs one million, which is not affordable for ordinary people."

The main breakthrough of this technology is a synthetic protein molecule with a special structure of concentric rings, which can give blood vessels extremely strong elasticity and pulling ability, so that they can expand and contract with the flow of blood.

In the minds of the public, artificial organs are definitely not as good as original organs.

As for the specific number, it depends on the medical insurance reimbursement situation.

Lu Tingfeng breathed a sigh of relief. Fortunately, the boss didn't set a super low price for such high-tech equipment, otherwise he would have cried to death.

Wei Kang thought for a moment and then said: "The cost of an artificial heart is still quite high. Besides, there are not many end-stage heart failure patients who can meet the transplant criteria. Clinical trials have not been carried out yet. It is too early to discuss the price. We will see when the time comes.

Let’s determine how the market will price it.”

"Mr. Wei, with such an artificial heart, how many heart failure patients can be saved?"

Wei Kang was speechless when he saw Lu Tingfeng's appearance.

Elastin molecules are stacked layer by layer to form a solid blood vessel wall, and the outer layer is wrapped in a sheath structure. After implantation into the human body, this part of the structure will gradually disappear, forming a highly organized bionic blood vessel.

Suddenly there was a knock on the door.

First of all, it uses high-strength bionic materials. The structure is very similar to the natural heart. It can also automatically sense and adjust the blood flow to adapt to the needs of the human body. In this way, the power of the artificial heart is reduced to 3W, which can be said to be qualitative.

improve.

After the patient has an artificial heart implanted, he only needs to carry a battery pack the size of a power bank with him, and it can be automatically charged to keep the artificial heart running 24 hours a day. It can also be placed on the bedside for charging at night, which is very convenient.

Sanqing's artificial blood vessels are made of bionic materials and have a complex structure that is very similar to natural blood vessels. After being implanted in the human body, over time, they will become the same as natural blood vessels in terms of appearance, behavior and function.

Perhaps it can also reduce organ smuggling activities and suppress the rampant black market.

Mainly because these projects are nothing new. The research in reality is already very mature. Not only has there been a breakthrough from 0 to 1, but it has also developed from 1 to 10, but it has not yet developed from 10 to 100.

“This penetration force is three orders of magnitude smaller than the minimum penetration force of artificial microneedles, which is 10 millinewtons, and six orders of magnitude smaller than the penetration force of ordinary syringe needles, which is more than ten Newtons.”

The external equipment is even more cumbersome. Patients need to carry a set of 4 kilograms of equipment to move around, including a controller, a set of batteries and other driving devices, and they are not allowed to engage in sports.

"It is conceivable that the market price is like this. If you want to transplant an artificial heart, it is impossible to even think about it if you don't have 1.8 million yuan."

It seems that he is not going to work, but a general heading to the battlefield.

The thinner the artificial blood vessels, the more expensive they are. A 15-centimeter artificial blood vessel with an inner diameter of 8 mm is worth 4,000 yuan, and an artificial blood vessel with an inner diameter of 4 mm can easily cost tens of thousands.

But so far, artificial blood vessels made of these polymer materials have various problems and cannot meet the high standards of clinical application.

The second step is to remove the power cord. An external power pack can charge the artificial heart wirelessly, as long as it is kept within 3 meters.

Wei Kang chuckled: "It's still early for the baby. Aren't you preparing for it? It's not like you're pregnant."

But those are all reusable testing equipment, such as biochemical detectors, B-ultrasound, CT, MRI, capsule gastroscopy, etc., which are used on patients many times a day and are essential for disease diagnosis. Naturally, the price should not be too expensive.

.

Among them, the organs are donated free of charge, and the main expenses are spent on pre- and post-treatment examinations, hospitalization, surgical expenses, etc. Even if the transplant is successful, the patient will have to take anti-rejection drugs for a long time, and the annual drug cost will be 30,000-40,000.

"This time, I hope nothing will happen to you again."

Next, the two discussed the situation of the project for a while, and then Lu Tingfeng got up and left.

Lu Tingfeng shook his head and sighed: "Damn mosquitoes, no wonder they don't even notice when they bite people."

The heart weighs 900 grams, which is 2-3 times the weight of a healthy human heart.

The human body's healthy heart, with a power of only 1.5W, can complete the same work and beat the artificial heart to nothing in seconds.

It was Sun Chengren who appeared at the door. He held Wei Kang's arm with a smile and sat down on the sofa in the reception area.

These are mainly caused by exogenous implanted materials triggering immune system attacks and inflammatory reactions, thereby inducing oxidative degradation.

"That's natural," Wei Kang said slowly, pointing to the anatomical diagram of the mosquito's mouthparts and comparing it with the drawing of the microneedle.

"If such a special needle is inserted with an almost undetectable force, can there be no difference in human feelings?"

The average cost of an organ transplant is around 500,000 to 600,000 yuan, and if there is transplant rejection, it will be even higher.

Therefore, between 300,000 and 500,000 is almost the bottom line in his heart.

This will undoubtedly prolong the precious survival time of patients and give them a greater chance of waiting for suitable organs.

******

“Tuk-tuk!”

The first two times he suffered a myocardial infarction, he was sent to the hospital twice, which directly contributed to the birth of Sanqing Clinic.

As long as the price is lower and many patients cannot wait, they will choose to install an artificial organ for transition.

Wei Kang believes that with such strong performance of artificial hearts and artificial blood vessels, there will be absolutely no other manufacturers in this market.

As for the artificial heart, after two or three generations of development, it has long been used in clinical treatment.

He immediately came forward in surprise: "Uncle Sun, are you back to work after the holiday?"

Generally speaking, after medical insurance reimbursement, the final self-care cost of the patient is about 150,000-200,000.

Because the artificial heart is a battery-powered pump head that needs to be connected to a power cord from inside the body and outside the body, you can imagine how much of a burden this entire set of equipment will bring to the patient.

However, in many places now, part of the cost of organ transplantation can be reimbursed, including surgical costs and part of the medication.

The more Lu Tingfeng read this information, the more frightened he became, and at the same time he became more joyful.

"That's when I learned the good news." Sun Chengren looked at Wei Kang, the loving light in his eyes flashing: "I watched you step by step, your career became bigger and stronger, and you found a good wife to get married soon.

It’s great to have children again.”

The main problem is that it can only be used for large blood vessel replacement surgeries and cannot meet the needs of small-diameter artificial blood vessels.

"Sure enough, whether it is painless to suck blood or mosquitoes are relatively strong, it is definitely a perfect example created by nature."

Logically speaking, the price of artificial organs should be lower than the cost of organ transplantation.

Wei Kang thought silently for a few seconds and felt that there should be no more problems.

"You see, a mosquito has a row of tiny and fine serrated structures on the outside and inside of its lower jaw. The more micro-serrated teeth there are, the stronger its ability to penetrate the skin. At the same time, the tips of the upper lip and lower jaw are also very sharp."

Even if the price is lowered a little, it can benefit the majority of patients and reduce the burden on medical insurance. This is called water.

To put it bluntly, in this situation, even a pig should know that health is the most important thing.

In fact, Wei Kang was also hesitant and didn't want to set the price now, but he also had a bottom line in mind.

In the past, anti-cancer drugs were sold for 200,000 yuan. Over the past few years, although the price has been gradually reduced, they still cost more than 100,000 yuan.
To be continued...
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