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Chapter 457 Cloning Organs (please vote for this chapter)(1/2)

"Artificial organs?"

He Ao stared at Coles in front of him, "Is it an animal... or..."

"Human organs," Coles took over from Ho, "to be precise, they are human cloned organs."

He glanced at He Ao and continued to explain,

"We all know that the human body develops from a single cell, a fertilized egg.

"Throughout the entire development process, the fertilized egg continues to divide and multiply.

"The proliferated cells differentiate into different limbs and organs. For example, some differentiate into skin cells and kidney cells, and some differentiate into red blood cells and white blood cells.

"Through these differentiations in adapting to the environment, our current complex human structure was ultimately formed.

"Generally speaking, it is basically impossible for cells that have been highly differentiated to transform into cells with completely different functional properties. For example, it is almost impossible for skin cells to directly transform into kidney cells.

"This is also a means for the body to maintain its own stability. Different cells have different highly specialized functions and cannot be converted at will. They form an organic whole and ultimately maintain the normal operation of the entire body.

"In contrast to this kind of differentiated cells that have differentiated and cannot continue to change shapes freely, there is also a kind of 'stem cell' in our body that has not yet differentiated, or has a relatively low degree of differentiation, and can differentiate again into different cells.

"For example, the hematopoietic stem cells present in our bone marrow can differentiate into red blood cells, white blood cells and platelets. Under certain conditions, hematopoietic stem cells can also differentiate into organ cells.

"The existence of stem cells allows us to 'repair' the injured bodies of some patients to a certain extent. Of course, we can also do some 'more cutting-edge' things, such as 'cloning'."

Having said this, Coles glanced at He Ao again, as if he wanted to see if He Ao understood.

But soon he realized that he had made a mistake in teaching and educating people, and actually began to explain the principles to He Ao in detail.

He shook his head, condensed his words, and continued,

"According to the order of differentiation potential from high to low, we divide stem cells into totipotent stem cells, multipotent stem cells and unipotent stem cells.

"The hematopoietic stem cells we just mentioned are pluripotent stem cells. Of course, to meet the requirements for cloning, pluripotent stem cells are not enough, and totipotent stem cells are needed.

"As the name suggests, it is a stem cell that can differentiate into all human cells.

"Theoretically, if the body's somatic cells are induced back into totipotent stem cells, and then the totipotent stem cells are stimulated to differentiate, we have the opportunity to 'clone' a person."

"It seems that the development of this technology has encountered difficulties."

He Ao said calmly.

If the technology of human cloning is successful, it will definitely be explosive news. Even after many years, someone will mention it, but there is no relevant information in the combined memories of his multiple characters.

"The technology of inducing somatic cells back into totipotent stem cells is now very mature, but when it comes to inducing differentiation of totipotent stem cells in vitro, everyone is stumped."

Coles nodded and continued to explain,

"Currently, the academic community has not attempted to 'clone humans'. The current mainstream 'exploration' is to clone organs, which can help treat many organ diseases and has no moral and ethical obstacles.

"But this step has stuck with federal biologists for hundreds of years. In the process of coaxing totipotent stem cells into specific organs, some strange problems always occur.

"For example, the 'organs' that grow out are not in the shape of an organ at all, or they have a specific 'organ' shape but no corresponding organ function."

"And here, I need to mention a top-secret project that Qunxing Pharmaceutical had to suspend fifty years ago. This project has not been declassified. Originally, I should not have access to this project,"

Coles said with a smile, "But my teacher was one of the last researchers recruited into this project. When I was studying with him, I accidentally heard a few words about these projects.

"Of course, I didn't care about it at that time. It wasn't until I joined the Mars Project and performed the surgery at the institute that I remembered this project that I had only heard some fragments of by chance.

"In those clips, Qunxing Pharmaceutical seems to have achieved some kind of breakthrough in 'organ cloning', and the project even progressed to the point of recruiting 'volunteers' for organ transplant experiments.

“But my teacher signed a confidentiality agreement, and he would not and could not tell me the content of this project. However, I followed the clues and found the family members of the ‘volunteers’ who participated in the project.

"Most of these volunteers came from poor families and could not afford expensive medical expenses, so they came to be volunteers. The confidentiality agreement was optional for them, so it was easy for me to find out about the project."

Speaking of this, Coles sounded a little emotional,

“First of all, I learned from the families of these ‘volunteers’ that almost all the volunteers who participated in the ‘experiment’ died, and the longest one did not live for more than a year.

“I found some agreements signed by the original volunteers, as well as some of the situations described by the volunteers’ family members, which roughly restored the original events.

"About fifty years ago, Qunxing Pharmaceutical most likely induced the differentiation of organs with normal shapes and functions. This was an epoch-making achievement. The group quickly advanced the project to human trials.

“But reality quickly poured cold water on the entire project.

"This kind of induced organ is prone to failure, and its lifespan is much lower than that of normal organs. After transplantation into the patient's body, the patient can live normally for a few months at most before dying due to rapid organ failure. Most patients do not live for more than a year.

.

“The group should have also conducted research on this aspect, but they ultimately failed to solve this problem, and the poor clinical results forced the group to suspend the entire project.

"But the group has not completely given up on the project."

At this point, Coles' meaning is already very clear.

He Ao looked up at him, "So you think that the 'Clone Organ' project and the Mars Project are integrated, and part of the results of the Mars Project have solved the problem of organ failure in the 'Clone Organ' project?"

But why did the institute put cloned organs into the bodies of those ‘volunteers’?

Obviously, those organs were not cloned for these volunteers.

At this time, He Ao's thoughts paused, and an idea appeared in his mind.

"I don't know how they solved this problem,"

Coles said slowly, "But they should have used the bodies of those 'patients', that silver metal box, and those medicines given to the 'patients', which should contain some key influencing factors that I don't know.

"

really,

He Ao looked out the window, and weak people were slowly walking towards the hospital with a huge mouth under the night.

The ‘volunteers’ recruited by the institute are actually ‘living petri dishes’.

Judging from Coles' description, 'cultivating' those cloned organs in the body causes great damage to the body and is a life-span-destroying thing.

In other words, the institute's high "volunteer subsidies" are "life-saving money" paid to those who volunteer and are short of money.

He Ao recalled Pat's memory of seeing an endless stream of people coming to participate in 'research' when he first entered the institute.

There are many people in this city, like Pat, who have lost their source of income due to unemployment, but are still burdened with high loans and huge life pressure.

"As for the use and origin of those cloned organs, I don't know. These are the ones I have access to. This is all I know."

Coles, who was sitting opposite, said hoarsely. Saying so many words in a short period of time seemed to be a burden on his body. He picked up the milk and took a slow sip.

He Ao came back to his senses and continued to focus on Coles. This question and answer should come to an end.

He took out a transparent test tube filled with milky white liquid from his arms, which was what he obtained from the 'Shadow'.

"Do you recognize this?"

he asked softly.

"This is the 'Elixir of Life',"

Coles took a closer look at the test tube, "This is a potion traded by the institute that can quickly restore vitality. According to Reid, even people who are seriously injured and on the verge of death can quickly recover from their injuries by drinking this potion.

This potion seems to be a by-product of the Mars Project, but it cannot extend life."

"The institute has a lot of this potion?"

Heao asked.

"Not much," Coles shook his head. "This kind of potion is very rare and basically has no market price. The research institute usually uses it to pay some powerful people, or to barter on the underground black market."

"Is that so?"

He Ao glanced at the potion in his hand and put it away.

Judging from the damage done to the body by the 'Nightcrawler' talent sequence, this life potion should be very useful for 'Shadow', so he has been reluctant to use it and only took it out before he died.

After the potion was completely put back, He Ao raised his head again and asked, "Where is this kind of 'life potion' usually hidden in the research institute?"

"In the 'safe' at the bottom of the institute," Coles replied slowly, then he paused and added, "All the data in the institute are also in that safe."

"Thank you for informing me."

He Ao stood up with a smile.

"fine."

Coles felt relieved and quickly stood up. He just wanted to leave here quickly.

But soon, He Ao's next words made him feel excited again.

"I still have two small favors that I need your help with."

——

Under the stars at night, Zhimei Hospital still has bright lights on.

Even late at night, many departments in this hospital are still operating normally.

He Ao and Coles walked together, walking slowly on the road in front of Qunxing Zhimei Hospital.

The narrow roads are crowded with various small vendors.

Densely packed stalls are arranged at random under the street lights.

"Orange juice, freshly squeezed orange juice that is sour, sweet and nutritious."
To be continued...
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