Chapter 25 Development of therapeutic agents
Among these four questions, the first three are technical issues, while the last one is outside the technical scope.
To solve the fourth problem, he had to have an experimental site located in the village so that he could rationalize his research.
This step is to take the initiative to put your experiment under the nose of the village and give the village a briefing to reduce the resistance that may be encountered during subsequent releases.
So Yayoi returned to the village, wasted his energy, and did not hesitate to sell his appearance (cute), and borrowed a clearing from the group of female veterinarians in the animal-taught and recuperation class.
Although the muscles are a little exaggerated, these veterinary ladies are quite easy to talk to.
Since returning to Konoha with Tsunade, Yayoi has been hiding among all classes in the medical department for a long time.
With his harmless appearance, he had long been familiar with these young men and sisters in the medical department.
The veterinarians all know that he is Tsunade's disciple, and have seen his superb level of palm art many times, and have a high evaluation of him.
Therefore, when he learned that Yayoi wanted to develop a therapeutic agent, the squad leader of the animal taming sanitation class not only did not underestimate him, but instead lent him a large open space.
Not only that, after learning about his needs for experimental rabbits, he also friendly sponsored some of his excellent experimental rabbit species.
He also enthusiastically said: If you don’t have time to train, come to her again, and the price is discounted.
After accepting these rabbits, Yayoi felt that the rabbit species looked very familiar as the more he looked.
He carefully identified it, but was surprised to find that the appearance of these rabbits looked very similar to the experimental rabbit species "Japanese Big-eared White Rabbit" commonly found in laboratories in previous lives.
This rabbit is a medium-sized, flesh-based rabbit based on Chinese white rabbits and is bred.
It has fast growth, strong reproductive ability, good maternity, large lactation, good adaptability, cold resistance, rough feeding resistance, excellent cortex and good meat quality.
Because of the large ears, clear blood vessels, easy to collect blood and inject blood, the experimental operation effect is ideal, so it is often used as experimental rabbits.
After the long-term cultivation of ninjas in the animal-taught and recuperation class, I don’t know what ninjutsu was used. The rabbit’s reproductive ability is nearly twice as fast as that of its peers on Earth.
These cute little rabbits can be regarded as part of Yayoi's urgent need.
Since the experimental site and experimental animals are already available, the development of healing agents can be officially put on the agenda.
Generally speaking, after a scientific research project is established and the research direction is determined, the first thing you have to do is to read the literature in the relevant direction.
The first purpose of this is to find out whether there are any ready-made scientific research results in the academic community that can be used directly to reduce duplicate work. This is also the reason why the more awesome academic papers are cited.
Another purpose is to prevent collisions with peers.
What Yayoi is doing now is to consult a lot of information from the Medical Department and Orochimaru, similar to the work of reading documents.
He is in the ninja world, so he is naturally not worried about colliding with any colleagues. The ninja world does not pay attention to any intellectual property rights, and it is pirated and authentic.
At the same time, he was also sure that Konoha did not have such a powerful cure medicine at this time.
The purpose of his reading of these materials was mainly to find ideas to solve three technical problems.
After half a month of crazy reading, Yayoi finally found a solution to the first two problems from some unpopular materials.
The first question is about how to actively refine the special Yang Dun Chakra.
The information to solve this problem comes from Konoha Medical Department, which is a conjecture about the mechanism of refining and use of yang chakra and promoting self-healing of injured cells when medical ninjas are used for a long time.
If you guessed correctly, the source of this data may be traced back to the second generation of Naruto, and is one of the by-products of studying Hashirama cells.
At the same time, it is closely related to Konoha's large-scale medical ninjutsu "The Art of Treating and Regeneration", and is the basis of the forbidden technique "creating and regeneration" developed by Tsunade later.
The second question is how to solve the source of tissue fluid or blood.
The key to solving this problem lies in promoting the body's metabolism and strengthening hematopoietic function.
In the scientific theories of previous lives, there are two types of hematopoietic growth factors: "colony stimulator" and "interleukin", which can act on hematopoietic precursor cells and lymphocytes to promote their differentiation and maturation.
There are similar records in Orochimaru's research, and even directly developed related ninjutsu to achieve his goal of excessive blood collection.
This ninjutsu did not consider the subject's body, and it would cause great harm to the human body, but it was very consistent with Orochimaru's usual practice of treating the experimental subject as a consumable.
But Yayoi wanted to use this technique on himself, so he naturally could not be so simple and crude.
This requires improvement to weaken the side effects of ninjutsu.
The idea of improvement is quite simple: weakening the effect of the technique itself can naturally reduce the damage it causes to the body.
It took another week for Yayoi to weaken the technique to a point where his body could withstand it.
After the two key problems are solved, the therapeutic agent can be directly configured.
The first batch of potions were very effective.
In the experimental group, several experimental rabbits suffered different forms of damage: internal organ rupture, severe concussion, electric shock, burns, and knife injuries.
After taking the drug, most experimental rabbits recovered their health except for a few individuals with very weak vital signs, and did not appear to have any obvious toxic side effects.
The only disadvantage of this batch of medicines is that it has been stored for too short.
When anticoagulant is added, it can only be stored for one to two days at most.
Even if stored in a low temperature environment, the validity period can only be extended to two weeks.
However, even though the therapeutic agent is not perfect, it has met Yayoi's expectations.
His main purpose of developing therapeutic agents is three:
First, it highlights one's own talent to show one's own value, and builds oneself from the identity of Tsunade disciples into Tsunade's second (medical aspects), seizes a certain position in Konoha's medical system, and gains a little qualification to talk to the top (official).
The second is to create a network of relationships, use your medical ninja identity, make friends with injured and patients, manage certain interpersonal relationships, and gain enough voice in the village (civilian).
The third is to obtain a large amount of financial income to fund your own research.
There is another reason why the agent is not improved, that is:
During the drug development process this month, Yayoi had spent all the money he had saved and even owed several veterinarians foreign debts.
Even the materials equipped with anticoagulants are misappropriated by Orochimaru Laboratory's inventory.
Chapter completed!