Chapter 754: Thalassemia
With the arrival of Tian Bing, the number of people in the ion channel laboratory expanded rapidly.
In a row, Yang Rui dug out three calfs, namely Tian Bing and Jiao Yangping from Tsinghua University, and Wang Sisheng from Beili.
Among them, Jiao Yangping will become a future academy, and he is very powerful. This can be said to be the pinnacle of Chinese scholars. After reading it for 30 years, there are still quite few Chinese academicians, and even fewer are majoring in biology.
Wang Sisheng from Beijing Institute of Science and Technology has no experience in studying or giving lectures, but he can still reach the level of the Thousand People Plan and is also a relatively large calf.
Yang Rui also quickly raised the research on genome and cloning.
Not only Yang Rui, Xu Zhengping, Professor Cai, Dean Liu and others were also excited to scratch their heads.
They did not expect to catch a great man who would become an academician or a scholar in the Yangtze River in the future, but during this period of time, domestic first-class scholars themselves are scarce.
It is necessary to wait until a large number of scholars trained by American imperialism return to China, the number of first-class scholars in China can barely exceed the number of giant pandas of the same period.
In a certain professional field, the giant panda still wins.
Just the three people brought by Yang Rui are now the backbone of Tsinghua University and Peking University, so naturally they are the backbone of Peking University. They can steadily rank before 5% of the school's professor sequence at any school except Tsinghua University and Peking University, and are the targets that all schools will win over. Even at Peking University, Tian Bing, Jiao Yangping and Wang Sisheng are also high-level scholars, and they are worth the effort to win over.
Of course, the calves are calves after all, and they are not as good as winning over at any cost. Yang Rui was able to pull them in, which made Professor Cai and Dean Liu very happy, but it was not necessary to let them pull them by themselves.
What's more, there must be a certain opportunity to attract people.
It should be said that the publication of "Genomics" and the promotion of "Chicago Reading Newspaper" have given scholars who have switched to the Ion Channel Laboratory sufficient reasons to change jobs.
In this era, transferring jobs because of money is a reason that can only be said privately. In the open market, this is a very immoral behavior, and the university academic circle is destined to be a small circle. Therefore, even if there is sufficient research funding, only elementary scholars who are forced to do so will use it.
After reaching Tian Bing's age and reputation, the reason why he could change jobs was either because he had a broken talk with his old boss, or he could only leave for his lofty ideals and his pursuit of knowledge.
Nowadays, going to the author of "Genomics" is a pursuit of knowledge.
This is true for Tian Bing, Jiao Yangping, and so is Wang Sisheng.
The work in the ion channel laboratory has also become easier. Including Su Xiankai, Fan Zhenlong, Xu Zhengping, and Yang Rui's previous researcher has already six researchers, which is basically the same as the Huarui Laboratory.
These are all real researchers trained by Wang after many years of scientific research. Yang Rui stayed in the laboratory for a few days and was basically relieved.
Among the three newcomers, Tian Bing and Jiao Yangping are both completely academic schools. The experimental techniques and the way of filling out reports are familiar to Yang Rui. Wang Sisheng is slightly inferior and it is nothing. After Xu Zhengping took him for a few days, he became familiar with the working methods of the ion channel laboratory.
After a week, Yang Rui recruited two head dogs from the applicants - the treatment was comparable to that of Su Fan from Beiyan Agricultural College, and the recruitment work came to an end.
If you recruit more people, the ion channel laboratory will not be able to be blocked.
In fact, to this level, the workload of a laboratory has been quite large.
The three even brought a lot of work from their previous units - or benefits.
When Yang Rui was at work on Monday, he just arrived at the laboratory and saw a letter on the laboratory table.
Wang Sisheng smiled and put down the test tube and walked over, saying, "Mr. Yang, the invitation I received before was held by Peking Union Medical College Hospital and several universities and research institutes. It is nationwide and there are exactly three places. I would like to invite you and Professor Xu Zhengping to go together. Is it appropriate for you to see?"
Wang Sisheng is the youngest of the three new calves, about 36 or 37 years old, and looks a little pink. I don’t know that he is still a fresh graduate student. Of course, his age is abroad, which means he has just graduated.
Wang Sisheng took out good things to give gifts, and Yang Rui also intended to win over them and immediately said, "Okay, one day, you call Xu Zhengping and let's go and have a look together."
"The day after tomorrow, it is also the deadline for submitting articles. Then the meeting will be held in two days. The local area will be held at Union Hospital. Didn't they cooperate with the World Health Organization two years ago? The World Health Organization Disease Classification Center, where the meeting was held, and they stayed at Union Hospital's guesthouse. There was also a full buffet, and it was said that there was Western food." Wang Sisheng's focus was naturally behind. He showed the invitation letter in his hand and smiled: "The three of us took the formal invitation letter and could eat a buffet, and there were three vice couplets. One could bring one person in to listen to the lecture, but we could not speak or eat a buffet. Look, who is the best choice for the vice couplet?"
"Just discuss with Lao Xu." Yang Ruicai didn't care about this and just said curiously: "The guesthouse of Union Hospital also has a buffet now?"
"Isn't this popular? They definitely can't open external business like Huarui Stadium and can't make a profit. However, they do it regularly and everyone likes it." Wang Sisheng smiled and licked his lips, with some aftertaste.
Yang Rui smiled and said, "You seem to be going there often."
"How can I do it? Someone needs to invite me to go. This time, Peking Union Medical College was also an invitation coupon from a friend."
"So popular?"
"If you want to go, you must go casually, I almost went." Wang Sisheng smiled and shook his head, saying, "Now people recognize professors. It would be worthless to bring a deputy in front of them."
"Writing a few articles is just a professor, don't worry." Yang Rui patted Wang Sisheng's shoulder to comfort him.
Wang Sisheng smiled helplessly. He did see the speed of the ion channel laboratory's results and finally made a choice. Otherwise, competing for professors at Peking University would be much more difficult than Beijing Institute of Technology.
Three days passed in a flash.
Yang Rui, Wang Sisheng and Xu Zhengping, plus Zhao Pingchuan and three other researchers, Wang, got into two cars from Jielikang and went to the World Health Group Disease Classification Center of Union Hospital.
Zhao Pingchuan originally worked in Tangji Laboratory, but the scientific research team assigned to Yang Rui was working for a long time. After Yang Rui's ion channel laboratory was established, he still often asked Zhao Pingchuan to come over. After a long time, Zhao Pingchuan simply obtained Tangji's consent and transferred to the ion channel laboratory.
Unlike the few head dogs with staff recently recruited by Yang Rui, Zhao Pingchuan is just an ordinary Peking University student and has no considerations in terms of staffing and other aspects. He can change places if he wants to.
Moreover, compared with Tang Ji's following the rules, the large number of projects that appeared in Yang Rui's ion channel laboratory can also make better use of Zhao Pingchuan's mathematical ability. Since he arrived at the ion channel laboratory, Zhao Pingchuan has signed in the second author column of the paper many times.
"The venue of Union Hospital has arrived." The driver stopped the car steadily and got out quickly, as if welcoming foreign guests, helping Yang Rui and others open the door.
"Mr. Yang Rui!" The scholar guarding the door was wearing a white coat and looked over because of the shiny rush, but he screamed in surprise.
"Hello." Yang Rui looked at the other party with a confused look on his face.
"I have seen your photos and the news on TV." The white coat exposed the reason with a sentence, bent over and shook hands with Yang Rui, and said with a smile: "Director Yang can come to our Union, we are Peng Shenghui, Peng Shenghui, Director Yang, please come here."
While introducing himself, he took Yang Rui to walk 300 meters with him and sent him to the conference hall.
Wang Sisheng's eyes were staring brightly. He sat in the seat before giving Yang Rui a thumbs up and said, "Director Yang is famous and amazing."
"I've read martial arts books recently." Yang Rui smiled and made a fuss. He is naturally well-known. "CELL" and "Nature" are both world-class journals. There are not necessarily a few articles that can publish articles on them. Although the main job of a doctor is not necessarily to publish articles, publishing articles to produce results is still the most dazzling job. However, Yang Rui did not come here to show off, so he simply turned his speaking direction to the chat mode.
Except for a few people coming to say hello, Yang Rui was still having a very pleasant chat.
The good mood continued to the middle of the meeting. When the venue began to display many photos of patients, Yang Rui's expression became solemn.
The photos of the patient who has been printed are from many children and teenagers with deformed bodies, deformed abdomen, slender legs, and mutated heads.
"Disabling globin production anemia is a very large number of hereditary diseases found in my country in recent years, especially in Guangdong, Guangxi and Sichuan. The treatment of intermediate and severe globin production anemia is very difficult and requires long-term blood transfusion treatment. The complications caused by long-term blood transfusion have further increased the patient's mortality rate..." The doctor who made the report on the field then pointed to the few pictures in front of him and said: "These are several patients I have treated, ranging from 1 to 18 years old, mostly severe, manifested as swelling of the abdomen like a drum and deformation of the head..."
"The premature death rate of globin-producing anemia is very high because it is a cause of hereditary disease. Severe patients often die before the age of 15 to 20. The average age in our country is lower. The expensive treatment costs are on the one hand, and the shortage of medicine is on the other hand..."
"The main reason for premature death of patients with globin-induced dysplasia is the side effects of iron accumulation, because the body cannot produce enough hemoglobin and red blood cells, and patients often need blood transfusions. The resulting enrichment of iron will have a serious impact on the functions of various organs in the human body. Clinically, we need to use iron chelating drugs to remove iron. At present, the most commonly used and only iron chelating agent we can use is deferroamine. It was first used in clinical practice in 1963, causing a boom in research on iron chelating agents in the medical field, but unfortunately, until today, no new drugs have appeared..."
"Nevertheless, by studying the different clinical manifestations of DFO, that is, deferroamine, we are still able to dig deep into the potential of deferroamine. For example, the micro-syringe pump currently in use can improve drug distribution and accelerate iron transfer and metabolism... Through the above methods, we have been able to extend the average life span of patients by about two years..."
After the doctor finished the report, he did not receive much applause. Although his preparations were much richer than others, the result was not satisfactory.
Although clinically speaking, extending the average life expectancy of patients for two years is already a victory, but such victory is really humble when facing patients under the age of 20.
Yang Rui twisted his body uneasy and said, "Disconductive anemia is thalassemia."
"Yes, it is also called marine anemia." Wang Sisheng understood the relevant content and answered with an understanding.
Yang Rui said: "In 1982, the year before, when Hider studied hydroxypyridone compounds, didn't he discover a new iron chelating agent, deferrosterone? Didn't he make a drug?"
"Thalassemia is a genetic disease. The main disease is in Southeast Asia, and some black people in Africa. It is too late for European and American pharmaceutical companies to do cephalosporins, so how can we invest in this regard?" Wang Sisheng shook his head gently and said without hope: "The total number of patients with thalassemia is not large, and there are deferroamines used..."
"Severely ill patients cannot even survive at the age of 20, of course not many." Yang Rui curled his lips, silent on the surface, but felt extremely uncomfortable in his heart.
Chapter completed!