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Chapter seven hundred and sixty sixth flame red lips

Grace's appearance stirred up a rippling of microwaves in Huarui's laboratory.

There are many foreigners in Yanjing City, and many pursue fashion, but it is not easy to see those who are beautiful in shape and unique in taste.

At first glance, it seems that the outfits of female soldiers on the battlefield are a bit rough, but when you look closely, the large pieces of embroidery behind the jacket and the spliced ​​leather on the legs look extremely unique.

Wei Zhenxue commented on the red-haired and blue-eyed girl without hesitation through the window: "I was in the village, and when I saw four colors at a time, I encountered a leopard."

"You grew up in a courtyard. When did you live in the village?" Huang Mao knew Wei Zhenxue well and exposed him in one sentence.

Wei Zhenxue coughed and said, "My grandma lives in the village."

"Your grandma is all from the Coal Management Bureau." Huang Mao sighed, very worried about Wei Zhenxue's nonsense skills.

Wei Zhenxue coughed hard again and said, "What's wrong with the Coal Management Bureau? The Coal Management Bureau has a hometown that is not prosperous."

"It's okay to have a hometown, but your hometown is from Datong. Are there leopards in Datong?"

Wei Zhenxue's lungs were about to come out, and he said angrily: "It's purely against me, right? Why can't we have leopards? There's a leopard in our zoo in our zoo..."

Thinking about it, I felt that it was not matched with my previous words, Wei Zhenxue coughed again and continued: "The leopard from our Da*tong Zoo ran out and ran to our village for me to see it. Is it OK?"

"Okay, okay..."

"What else is there?"

"Just one."

"Tell me." Wei Zhenxue was angry all over.

Huang Mao took two steps back and said, "The leopard only has three colors."

"What?"

"Yellow, black and white, haven't you seen it at the zoo?" Huang Mao said while smiling.

Wei Zhenxue coughed hard, "I saw a leopard running out of the zoo in my grandma's hometown. It was definitely four colors. Maybe it was covered with coal ash. Yes, it must be coal ash."

"The coal ash is black..." Li Wenqiang asked in a low voice.

Wei Zhenxue wished he could cough out his lungs.

In the yard, Grace was also worried when she heard the deafening cough in the room and asked, "Did anyone have the flu? Or is it very serious pneumonia."

"No, they are playing games." Duan Bo, who went out to do research, lied against his conscience.

"Learn the sound of pneumonia?" Grace said with a rich imagination: "Is it a new project in your lab?"

"Of course not, they are just playing. Let's go to the laboratory here..." Duan Bo led the two of them into the laboratory with a little embarrassed attitude and then introduced their recent work.

Grace put her hand in her pants pocket, and she walked around the main laboratory in a handsome manner and asked, "Who is Yang Rui? I heard that he is the main researcher for deferrotonide, right?"

"Yes, Yang Rui's words, I haven't come today." Duan Bo looked at his watch and said, "He has only been here at noon in the past few days. Should you wait a little longer?"

"Of course, I'm here to see him." Grace said as she found a place to sit down and said, "You go and do it. I'll just wait for Yang Rui to come and see him by myself. By the way, what does he look like?"

"What does it look like..." Duan Bo recalled the description that suited Yang Rui and replied in writing: "Long and very upright."

The translation conceived and gave Grace a good translation.

Grace said incomprehensiblely: "What is that?"

"You will know when you see it." Duan Bo answered.

Two hours later, Yang Rui appeared, and Grace recognized her at first sight.

"I didn't expect that there was such a man in China." Grace leaned her head and looked at Yang Rui step by step with admiration.

At this time, Huang Mao was responsible for accompanying him. He said with a strange expression: "There are all kinds of men in the world, and there are hundreds of millions of people in China, and all kinds of men."

Grace shook her head and said, "Impossible."

Huang Mao was surprised: "Why?"

"I know scholars of the biology level or above, and there is no such good as Yang Rui." Grace used the adjectives given in the translation just now.

Duan Bo, who has a restrained personality, couldn't speak for a moment.

Grace stared at Yang Rui for a while before asking, "It was because you took three weeks to make 19 derivatives of deferrosterone?"

Yang Rui was also a little impressed by Grace's look, looked between her blue eyes and her high nose, and said, "Are you the expert Van Lunding called?"

"Yes, this is our Professor Grace Brian from Cambridge." Fan Lunding suddenly realized a deep sense of crisis. He stood directly between Yang Rui and Grace and said: "We can save some time to exchange greetings and use it to learn about Huarui Laboratory's work on deferrosterone."

"I think you mean my job." Yang Rui took credit on himself without hesitation, and what he said was the truth. In the process of developing the deferrosterone, except for the help of a few experimental dogs, he did all the work.

Van Lunding laughed twice: "Okay, your job..."

"Can I read your experimental records? Unless it's too confidential."

"It's indeed confidential. You can look at the part we selected." Yang Rui knew that someone would want to know his work, especially the observation of professionals. His experimental records were complete and could withstand investigation, but as a drug that had not been interviewed, he had no reason to disclose all the information to the other party.

"The filtered part is OK." Grace got the bound documents and quickly flipped through them.

Synthesizing a compound is extremely difficult, but the molecular formula and synthesis process are extremely simple.

"I want to ask a question." Grace put the document aside and said, "Why choose to make ferrosterone? For iron chelates, are HBED compounds and DFT compounds more promising?"

"Maybe, but I think it's more realistic to remove ferroster." Yang Rui shrugged and replied.

Grace held her chin with her hand, put on a styling, and thought for a moment: "If it were me, in order to make the product as soon as possible, I would choose LCL670. Its two phenolic hydroxyl groups and 4 N on the triazole ring form three chelating sites. In terms of the affinity of iron ions, it is not much different than deferrosterone, but its lipophilicity is stronger, ensuring the ability to enter the cell after oral absorption. No matter how you think about it, it is more realistic than deferrosterone."

Her string of words instantly made the research atmosphere in the laboratory strong. Several people looked at Yang Rui and wanted to hear how he answered.

Yang Rui just spread his hands and said, "I'm afraid that the specific performance of LCL670's lipophilicity in the human body will only be known after clinical trials. Before that, LCL670 is more difficult to synthesize, right?"

Grace smiled, looked at Yang Rui with a clear look, and said, "You can synthesize 19 kinds of ferrosterone compounds in 3 weeks. Isn't it easy to synthesize LCL670?"

Yang Rui was stunned. This sentence really hit his weakness.

19 kinds of ferrosterone compounds were synthesized in 3 weeks. Even if others say that Yang Rui did it quickly, it doesn’t matter. Anyway, I’m so good at doing it quickly, and you’re stupid at doing it slowly. You don’t need to say such subtext.

But Grace's problem is very sharp. Since Yang Rui is so powerful in synthesis, why didn't he synthesize a more difficult but seemingly more effective compound?

Moreover, Grace has a good vision. LCL670 will pass the review of the Drug Administration in future generations and become a powerful drug with the product name delaros. Its overall safety and efficacy are stronger than deferrosterone.

It is difficult for Yang Rui to explain this. He can't say that he is very worried about the risk of renal failure caused by dilarosili. It is the potential risk that dilarosili was discovered only two years after dilarosili was launched. Yang Rui has not even synthesized this drug, so how can he make a judgment.

From a later perspective, we re-examine deferrotonide and delaros, the latter is still better than the former, but the risk of renal failure is a very strong negative. Novartis conducted clinical trials that year, either good luck passed or conspiracy theories were covered up, and these uncertainties were avoided by Yang Rui.

It took several years and eventually failed in the third phase of clinical practice. This is the rhythm of the company going bankrupt.

Not to mention that Huarui Company currently has a third-party income of $10 million a year, even medium-sized pharmaceutical companies with annual revenue of hundreds of millions of dollars are often unable to bear the failure of the third phase of clinical practice.

In the field of pharmaceutical investments that have risen exponentially, most pharmaceutical companies will not even touch the second phase of clinical practice. They are more willing to sell drugs that have passed the first phase of clinical practice at a good price, and then let large companies bear higher risks and make greater profits.

After thinking for a long time, Yang Rui replied: "The drugs made of LCL670 are more complex and costly. I think Chinese patients, as well as most patients with horizons, need lower-priced drugs."

"But the drugs made of LCL670 will be more effective." Grace looked straight into Yang Rui's eyes.

"If we can make this expensive drug after many complicated procedures... I will still choose to deferrosterone. You may not have seen Chinese horizon patients. Many of them have not used deferrosterone. Even when they need deferrosterone, the expensive price will stop them." Yang Rui paused and said: "In China, in current China, prices are more important than efficacy. Cheap drugs can extend patients' lifespan longer than efficient drugs."

Yang Rui read and learned enough from the information collected by the hematologist Yong Xiaodong. At the same time, he also knew the past and present lives of the Diping patient in the mainland. Therefore, his answer was true and realistic.

Grace fell into a long silence.

The laboratory also fell into silence for a long time.

Suddenly, Grace reached out her hand, hooked Yang Rui's neck, and kissed her heavily.

The flames are red lips, intense and long.

"You are a true scholar, fighter, and have a kind heart." Grace said softly after she left Yang Rui.

But the surroundings remain silent, silence so much that it is silent.

Neither young or middle-aged or elderly people in 1984 have seen this.

Even Comrade Fan Lunding, a British man, had his eyes straight, like a locust tree struck by lightning.
Chapter completed!
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