"Your idea... will face a very important issue. If the US Congress, or any country's funding agency, cannot see our output, the genome program may be stopped..." Dalbeko obviously thought about the issue of whether to do technology first or sequencing first, but he did not make any decision.

"The human genome project will be very different from other projects," said Yang Rui.

"certainly."

"If the current technology is adopted, sequencing will be very, very long. Indeed, if we directly sequence and use existing technologies and tools, we may be able to get some results in the first year, 50,000 base pairs?" Yang Rui smiled disdainfully and said: "Our goal is 3 billion base pairs. With the current technical level, if we do not make a lot of investment, we will not be able to complete the entire project even if we have a budget of 15 years."

"But from the perspective of Congress and the people, we have at least 50,000 base pairs, which is a visible benefit, right? And in this process, we can continue to develop technology, and sequencing itself can also help us develop technology, right?"

Yang Rui said without hesitation: "It is impossible. Sequencing itself is a physical job. We need to pay attention to the sequencing method and also the results of the sequencing. As for sequencing itself, it has no meaning."

Dalbeco was a little surprised at Yang Rui's arbitrary decision, but he was also a person who had been in the front line for many years. If you think about it carefully, you had to admit: "What you said makes sense. But I think even Congress will ask us to develop technology while sequencing it."

"If I were asked to choose, I wouldn't recommend this." Yang Rui shook his head and said, "Even if we go all out, the results of the first and second year will be ugly. If that's the case, why should we come up with results? I want to say that we should not sequence even one base pair except for testing in the first, second, or even third year."

Not only Dalbeko, but Professor Cai and Tobiles were also stupid.

This is the first time that Yang Rui has put forward his own opinions. He is not agreeing with Dalbeko's opinions, but rather contrary to Dalbeko's opinions.

Yang Rui's performance at this time is decisive about the relationship between two people, as well as their future relationship and position.

Of course, his opinions were also very decisive.

Dalbeco couldn't help but think deeply, and after a while, he asked, "Why? If we do this, our pressure will increase greatly."

"As long as the project is established, such a huge project, even those who are eager for quick success and instant benefits will not require us to give results in one or two years. Therefore, we will completely give up base pair sequencing in advance and focus on technology. I think that although the pressure will increase, it will not increase too much. In the third year, the pressure may increase a lot. At that time, it is OK to do a certain amount of base pair sequencing." Yang Rui explained softly.

"Is it necessary?"

"It is very necessary." Yang Rui said: "We do not sequence any base pairs. We can explain to investors or the public that the technology-leading strategy we are now adopting. Our current preparation is to complete the sequencing of base pairs more quickly in the later stage and save money. Once we have performed sequencing, for example, in the first year, we have completed the sequencing of 50,000 base pairs, what is the result? Will investors and the public be happy?"

Dalbeco hesitated, "Can't it?"

"Of course not, because anyone can do this simple calculation. It took us a year to complete the sequencing of 500,000 base pairs, and 10 years to complete the sequencing of 500,000 base pairs. There are 5 million in 100 years, and 1,000 years to only 50 million in 1,000 years to reach a conclusion that the human genome plan is finished." Yang Rui took out his long-prepared big move.

Dalbeco was stunned and said in a flash: "We sequenced 50,000 base pairs in the first year, which does not mean that our progress will be the same next year. Our progress in the second year may be 1 million base pairs. We may be able to complete the sequencing of 10 million base pairs in the third year."

"Since that's the case, why don't we resequencing the second year? Ordinary people cannot predict the development speed of science and technology. They will use their salary increase to judge technological innovation, such as 10% progress, or more or more, double progress, but no one will believe in a 20-fold increase, and if I have to judge, a 50-fold increase can be achieved."

"You mean, using a technology-first strategy, you can get 50 times the rate in a year?"

"That's right, only by using this method can we complete the genome plan as quickly as possible and gain a competitive advantage." Yang Rui actually felt a little emotional. The human genome plan lasted for more than ten years and spent more than 2 billion US dollars to complete the sequencing of 2.3 billion base pairs of the human body for the first time.

However, by 2015, the cost of sequencing 2.3 billion base pairs of the human body has been reduced to US$99, and the time consumed is calculated in hours.

Even Dalbeco may not be foreseeable for this kind of technological innovation.

It should be said that Yang Rui used past experience to try to influence Dalbeko's decision.

Dalbeco was indeed affected.

If someone else said this, even Professor Cai, or even Professor Richard from the University of California, said this, Dalbeco would not be affected.

But Yang Rui is different. Yang Rui is the inventor of PCR, and Yang Rui is also the pioneer of genomics.

Dalbeco has been paying attention to Yang Rui's research from beginning to end. Currently, scholars who are engaged in genetic research have not paid attention to Yang Rui's work. The so-called name of the shadow man of the tree, Yang Rui's performance in the past two years, determines the value of his thoughts.

If Dalbeco had chosen, who was most qualified to estimate the development speed of genetic technology, Yang Rui might not be the first choice, but if Dalbeco wanted to make a choice between himself and Yang Rui, he would believe Yang Rui more.

The so-called professional expertise is that Dalbeko's research in the field of genes, especially in the field of genetic technology, is far less profound than Yang Rui's research, and Dalbeko is no longer young.

A scholar's research life can last for a long time, but those who rely on themselves, especially their intelligence and physical strength to complete research work are usually under 40 years old, or at least under 50 years old.

This is the golden age of scholars. Scholars over 50 years old can be a leading academic leader, a leading laboratory manager, and a leading project manager, but it is not suitable for the academic achievements of scholars whose energy, physical strength and intelligence are at their peak.

"How many years do you think we can catch up with the results of parallel technology using technology?" Dalbeco already had a tendency in his heart.

"Three years. If sequencing starts in the third year, it will not be a problem to complete the one-million-level base pair sequencing by the end of the third year. If sequencing is not carried out in the third year, there will be a chance to complete the tens of millions of sequencing starting in the first half of the fourth year." Yang Rui is very confident about this. The Human Genome Project is a very large project, which means it is a project with very abundant personnel and funds. As long as you choose the right direction, the results will be achieved very quickly.

"Your prediction is based, right?"

"certainly."

Dalbeco thought for a long time and admitted: "If you can really reach the sequencing speed of tens of millions, your solution may be really better."

He raised his head and said, "Would you like to write an article on this?"

"No problem." Yang Rui has been training for so long and is easy to write an article. As for the basis, it is not difficult to prove it.

"Our Peking University Conference fully cooperated." Professor Cai turned it into a cooperative project in a timely manner.

Yang Rui said indifferently: "Then let's do it in the ion channel laboratory."

Professor Cai nodded and said, "I agree."

Of course, Dalbeco didn't care. After confirming this matter, he started to ask more actively.
Chapter completed!