"Director Yang, where is it inappropriate?" Gu Qiang scratched his head.

"It's because it's so suitable." Yang Rui murmured to himself, "Did you form a complex under the conditions of the presence of detergent?"

"Yes, I've tested the ARgs complex you named, and can effectively couple it in the phospholipid bilayer."

Yang Rui looked up at Gu Qiang and asked again: "Has there been no decrease in coupling efficiency? I mean, in the presence of detergent."

During the first stage of research, detergents were also used to treat G protein-coupled receptors. However, unlike the second stage, in order to ensure the "purity" of G protein-coupled receptors, the second stage always requires the existence of detergents. This is a high requirement. The most important thing is that once the detergent is present, the coupling efficiency of G protein-coupled receptors will be greatly reduced and down to an outrageous level.

There are two ways to solve this problem. One is to complete a series of experiments before the coupling efficiency drops to unacceptable, and the other is to solve the problem of coupling efficiency decreases, or at least extend the time of high efficiency.

Yang Rui was about to come to Gu Qiang's experimental records and started to search.

I saw that Gu Qiang's experimental records were only a short page in this part.

Gu Qiang's answer was even simpler: "There was a decrease in the early stage. After I changed the solution, the problem of decreased coupling efficiency was solved."

Yang Rui's voice was about to tremble, and he pointed to Gu Qiang's experimental record and said, "You have changed to dodecyl maltoseside solution."

"Yes. However, it was later discovered that the complex formed in this way was unstable."

"Yes, it must be unstable."

Gu Qiang nodded and said, "Then I remembered the experiment I had done before. When I encountered similar situations, I used enzymes to solve them. So I added adenosine triphosphate bisphosphate, which just hydrolyzed the complex to avoid interaction with Gs."

"Yes, it just happened to be hydrolyzed." Yang Rui was speechless.

Gu Qiang said guiltily: "Is there something wrong? I did it all according to your plan, and there were no problems."

"The problem is that there is nothing wrong with it." Yang Rui stared at Gu Qiang for a long time and said, "Why did you do the plan smoothly?"

"Isn't it good to go smoothly?" Gu Qiang had a somewhat unruly personality, but he had been tamed by Yang Rui long ago, and he was a little nervous at this time.

Yang Rui recalled Gu Qiang's counterintuitive "one-pot stir-frying" technology and his precise experimental skills, and suddenly asked: "Have you browsed your circle of friends?"

Gu Qiang was stunned for a moment and said, "No friends are playing tricks on me."

"Okay." Yang Rui sighed and said, "Congratulations, another top paper has been made from you."

"Make it?" Gu Qiang was stunned.

"Yes, it's done." Yang Rui confirmed.

"It's really done?"

“It’s really done.”

"It's impossible, it's only a few days." Gu Qiang jumped excitedly, his cheeks flushed and red.

Yang Rui nodded in agreement and said, "I don't think it's possible, it's only been a few days."

"Is the second phase completed?"

"That's how the crystal structure of the composite is?"

"The crystal structure is made?"

Influenced by Gu Qiang's cheers, a group of researchers surrounded him.

Yang Rui was like a tour guide, telling a passionate story casually, saying: "Although some mathematical calculations and verification are still needed, the crystal structure is almost done."

A group of people looked at each other and finally ended up with a question: "How is that possible!"

Yang Rui sighed empathically, not knowing how to explain.

If you want to say that this story is destined to be a strange anecdote, it is also inseparable from Yang Rui. He gave him the secret to pass the level and gave the full set of plans.

Yang Rui did this to improve the speed and complete the second phase of the research as quickly as possible. Given a complete set of solutions, the researchers were able to make targeted modifications and tests.

However, given a complete set of plans, someone actually completed the plan in a few days, which is the most incredible thing.

Not to mention the Nobel Prize-level scientific research experiments, or the junior high school experiments, the teacher still provides a complete set of experimental plans. Can all students produce results?

If you find a middle school chemistry teacher to answer this question, he can tell a hundred strange experimental results, but none of them are real experimental results.

How many students can produce results for a slightly more difficult university experiment? One of the three is even if the students are studying hard.

In a weaker university, it is common to take an experimental class on organic chemistry and classes that have not produced any results.

Not to mention the difficulty of experimenting with the crystal structure of G protein-coupled receptors. Several major key points are the first thing to do is to use the correct detergent to control relatively appropriate concentrations. The requirements are relatively broad and easy to achieve, but this alone is not something that can be done by just pulling an experimental dog.

Next, complex crystals of G protein-coupled receptors should be generated at appropriate concentrations.

There are even fewer researchers who can make this step. If this is used as a graduation requirement for university experimental courses, 90% of undergraduates will have to cry.

Immediately afterwards, ensuring the coupling of composite crystals in the presence of detergent is another requirement.

Historically, Kobika discovered that dodecyl maltosene solution can solve the problem of coupling. It has not been recorded how long it took him to do so, but with full of malicious speculation, it is a little bit of a problem to try it for three or four years. Of course, it is not Kobika himself who tried it. Some of him are doctoral students and assistant researchers, but this can only show how many outstanding researchers' scientific research life has been wasted.

After solving the coupling, the remaining steps, including the hydrolysis of enzymes, are not a particularly waste of time, but in terms of normal historical processes, several months are always needed. Yang Rui operates the golden finger and reserves time according to two months.

However, all of these, all these golden fingers, the genius's inspiration suddenly appeared, and the hard work of the scholars, under the luck of the dog, are as ethereal as smoke and dust.

Gu Qiang made it step by step, and did it with more correct steps than trial and error steps, and it came out...

In Yang Rui's opinion, it's like you installed an extremely difficult stand-alone game and found a pass strategy online, and then... three lives to pass the level!

"I'll take a look." Yang Rui said and called out, "Su Xiankai, Fan Zhenlong, Tian Bing, that... Professor Manhai, Professor Tao Xuelin, you can also add it and do a repeat experiment according to Gu Qiang's experimental steps. Lao Xu, you and I will check the experimental records again. By the way, the experimental table is not allowed to move, and the garbage is not allowed to be dumped. All the packaging of used consumables must be recorded."

All the researchers whose names were pointed gathered together.

Gu Qiang still didn't realize his strong luck today, so he laughed and said, "There is no need for so many people, it's easy for me to do this experiment."

"Well, Gu Qiang, you can open another set of them yourself and do another set of repeated experiments." Yang Rui didn't dare to take it lightly. This was another Nobel Prize-level achievement, which was done in a few days. Who dares to believe it?

Gu Qiang changed the experiment table indifferently, took out various consumables again, started to do it, and said, "You said I'm afraid of other things, I'm the least afraid of doing experiments."

While saying that, Gu Qiang hummed a song.

Only Yang Rui, like facing a great enemy, stared at the various experimental tables in the laboratory, and his mind was changing.

The progress chart on the white wall is brand new, with only the bottom, and two participating laboratories added, namely the University of Melbourne in Australia and the Winter Institute in the United States, with progress bars of 2.7 and 1.6 respectively.

Yang Rui glanced at it and stopped looking at it. If the triple repeated test can prove the accuracy of the results, the progress bar of Peking University Ion Channel Laboratory will be approved as 100 points.
Chapter completed!