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Chapter 1316 The sense of looking up

"Hey, crystal structure diagram?" Marjorie is a professor of biology at Caroline Medical School and is not sensitive to vocabulary such as G-protein-coupled receptors.

The most common thing a professor at Caroline Medical School does is to read literature, especially those of scholars who are eligible to win the Nobel Prize.

For them, the Nobel Prize is an advantage and a burden.

The advantage is that Caroline Medical College has received a lot of funding, as well as the attention of high-end scholars from abroad, and the burden is caused by constant reading of literature.

Professors at Caroline Medical School read literature differently. Normal people read literatures, which they need to read. For example, if Yang Rui wants to read literature, they basically focus on G-protein-coupled receptors, PCR, genes, genetics and other fields. In short, they need to read what they need. Other fields are usually limited to understanding. At most, they can read a few CNS articles and just know it.

Professors at Caroline Medical College cannot read literature like this. They have to read CNS-level papers in the end. Whether it is their own field or not, they must read them, especially scholars who may win the Nobel Prize, and fields that may be published in the Nobel Prize must be included.

A person's time is limited, and scholars' time is even more so.

Nowadays, there are three or five laboratories in a slightly popular field. Professors of Caroline Medical College have to spend most of their time reading documents that are not related to their research, and the investment in scientific research itself can be imagined.

For Marjorie, he has gradually become tired of being a professor at Caroline Medical School, but the foundation laid over the years is still there.

Hearing the words "G protein-coupled receptor" and "crystal structure diagram", he was the first to wake up and hurriedly walked to the laboratory.

To be honest, if it weren't for what Yang Rui said, he wouldn't believe it.

As a professor of biology at Caroline Medical School, Marjoli and his most basic ability is to judge an academic direction, how long will it take to see the light of the light and how long will it take to see the results.

Of course, such judgment is definitely inaccurate, but there are also certain ranges.

Yang Rui's ion channel laboratory has just completed the clear composition of G-protein-coupled receptors - a few months for Wang's scientific research results, just now - Marjori believes that the basic time to obtain the crystal structure diagram should be more than three years, and it will be less than two years.

Such judgments are not a joke. Whether a laboratory should spend tens of millions of dollars and join such competitions often makes decisions based on such judgments:

It is expected that the crystal structure of G protein-coupled receptors will be revealed in the next two to five years. Based on the capabilities of this laboratory, we may complete the project in the next two to four years. Joining the relevant competition will have a certain winning rate, so we can consider joining the competition.

The Peking University Ion Channel Laboratory completed the crystal structure of the G-protein coupled receptor in a few months, which means that all other laboratories participating in this project in the world have suffered huge losses.

At the same time, it also means that the resources of the whole society have been saved greatly.

However, Marjoli was not concerned with the savings. He couldn't help but feel nervous when he thought of the laboratory where he was working on related projects.

The others' reactions were slower, but they also opened their eyes one after another and asked, "Did you make a clear crystal structure diagram? So fast?"

"We actually completed the relevant research several months ago, but it took a long time to do the repeated experiments." Yang Rui said while leaving everyone to the laboratory.

It is actually not much to do repeated experiments in a few months. Some verification experiments are laborious, and some have been used for several years.

However, Yang Rui's words fell into the ears of those who are interested, but they were as terrifying as thunder.

I started doing repeated experiments a few months ago. When did the results come from?

It turns out that many laboratories around the world have been doing in vain in recent months?

Marjorie felt cruel when she thought about it.

However, the scientific research world is so cruel. Those who feel cruel die in the vast competition, and those who survive can only grit their teeth and persevere.

"Let me see what you did." Marjorie asked.

Yang Rui smiled and said, "What you see now is the result of repeated experiments. In addition, our thesis has been written."

Papers are experimental records after sorting and sublimation, and are naturally the most suitable for reading.

Marjori didn't say much, so he took it over and started reading it quickly.

Lantherot, behind him, also came from Catherine Medical College. He also slowly picked up a thick paper and read it quietly.

Such papers are time-consuming to read. Generally speaking, Marjorie is used to skipping reading.

But this time, he was a little reluctant.

This is a king-level scientific research project.

It would be a waste if you don’t look at the papers of King-level scientific research projects carefully.

Yang Rui was not in a hurry, so he asked someone to make tea for them, and sat next to him.

After drinking a few cups of tea, Marjoli finally raised his head and said, "Director Yang, can we talk to the researchers who are doing specific operations?"

"Of course." Yang Rui agreed with all his requests.

Today is here to show off his skills, but he hesitated after he stood up and shouted, "Gu Qiang, how are you remembering there?"

"I'm done." Gu Qiang replied in a low voice.

"Then come here, Su Xiankai, Fan Zhenlong... you all come here too." Yang Rui pointed the names of several people in a row.

"I see that the name of Researcher Gu Qiang is included in the paper." Marjorie got used to becoming a natural person and began to trace the experiment's completion and asked: "Researcher Gu Qiang, can you introduce the experimental process easily?"

Gu Qiang said obediently: "Did I generate a complex under the condition of the presence of a detergent? We named this complex the ARgs complex. After testing, I found that it can effectively couple in the phospholipid bilayer..."

"Wait, it is necessary to use detergents. Why do we need to form a complex under the conditions of the presence of detergents?" Marjori had a question in his first sentence.

Gu Qiang looked at Yang Rui and did not get the answer. He shrugged and said, "Because to ensure the purity of G protein, a detergent must be needed. We need a pure complex, so we can only do it under the conditions where the detergent is present."

"Even if the coupling efficiency is greatly reduced?"

"Of course." Gu Qiang also studied this issue at the beginning.

However, Marjorie has read more literature than Gu Qiang, and immediately asked: "Have you considered a different approach? For example, instead of using detergent, you can use physical or other methods to ensure the purity of G protein. I saw that multiple laboratories are trying this. How did you make a judgment?"

Gu Qiang opened his mouth, but didn't know how to answer.

He had never thought about this problem before.

The experimental plan given to him was to synthesize under the condition of the presence of detergent. Gu Qiang's theoretical system was weak and he had never considered to bypass this point.

Of course, his experiment was done too quickly and he quickly broke through this difficulty.

However, Marjori's question is also very typical. Gu Qiang thought for a moment and said to the truth: "This is my task at that time."

"You mean, Mr. Yang Rui arranges your plan?"

"yes."

Marjoli's eyes naturally turned to Yang Rui and asked, "Mr. Yang Rui, what did you think about it at that time?"

“I didn’t think about it.”

"kindness?"

"I arranged for others to try other solutions." Yang Rui said calmly: "We have invested quite a lot in G protein-coupled receptors."

Marjoli immediately understood and said, "Do you have multiple groups trying?"

"Of course. Su Xiankai and Fan Zhenlong were both in different groups at that time." Yang Rui answered in the simplest way.

That's how it was.

As the head of the laboratory, Yang Rui proposed a plan and arranged different researchers to perform verification. This is the most basic laboratory operation plan.

It's like Yang Rui leading a team to march. When he encounters a fork in the road, he can certainly decide his actions based on experience and theory, but he can also send someone to explore directly.

Gu Qiang was lucky enough to find the right direction, that's all.

Marjorie knew it in his mind after a few simple words.

He asked Gu Qiang a few more questions and slowly turned the topic to Yang Rui.

Academic achievements are attributed to IQ and distributed according to IQ. The hard work itself is worthless.

Yang Rui had questions and answers, and soon established a corresponding image in everyone's hearts.

As the problem deepened, some scholars began to fail to keep up with the conversation between Ma Qiaoli and Yang Rui, and most people began to focus their thoughts on the project itself.

"Peking University Ion Channel Laboratory parsed the crystal structure of G-protein-coupled receptors."

"Yang Rui's research is advancing very quickly."

"incredible."

The lowly discussions of several people gradually turned into discussions among a group of people.

This is really too shocking, so everyone's problems are stacked up.

However, Marjoli asked questions on his own regardless of what others thought. From his perspective, understanding Yang Rui has become a necessary homework now.

The G-protein-coupled receptor represented by Wang Qi was overcome by Yang Rui in two difficulties in a row. As long as Ma Qiaoli thought about the sensation that could cause, he had to be careful and careful whenever he thought about the sensation that the news could spread.

However, as he spoke, the scene in the backyard suddenly appeared in Marjori's mind.

"Mr. Yang Rui, I remember, we seemed to talk about three-dimensional structure before? Is it the three-dimensional structure of G protein coupled receptor? Have you gotten involved?" As soon as Marjori said, the surroundings became quiet.

The scholars present seemed to have been reminded, and their expressions were wrong when they looked at Yang Rui.

Think about it, if the repeated experiments of crystal structures started a few months ago, it means that the main project ended a few months ago. For such a long time, it is impossible for the Peking University Ion Channel Laboratory to only do repeated experiments and not do new research.

Then, new research...

Is the new research the three-dimensional structure of G protein-coupled receptors?
Chapter completed!
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