Because of the tight time and heavy tasks, the building of the Clinical Experimental Center of Hedong University uses the ready-made School of Science building.

This building was originally intended for teaching students in the School of Science, and part of it is used as the classroom for teachers, but now it has been occupied... Everyone is actually very happy.

After all, a new project has been implemented. For all the teachers and students of Hedong University, Yang Rui’s clinical experiment center is located in the school. It is a great thing no matter how you look at it, especially the teachers and students who are studying, and they are extremely looking forward to it.

The current distribution system determines that the school’s quality is more important than the teaching quality.

A good school will have good units to ask for people, while a bad school will connect with units that no one will go to. It has a very pure working relationship and occasionally something will happen. However, for most students, bringing glory to the school is really a matter of serving everyone.

If the school is not qualified enough, the other party will not recruit people at all. Do you think you are of your own quality and the genius of this year? Will the leaders of government units and state-owned enterprises care?

A provincial enterprise will be very proud that it has grabbed a student from Peking University this year and two students from Peking University, but it will be very shy to say that we have solved the work of 12 children from the technical secondary school in our unit, of course, it was solved under a very rigorous review system...

Even after entering the unit, the university where the first degree is located will still be mentioned on different occasions, and it will play a big role from time to time. Especially in vertical systems, such as electricity, postal, telecommunications, taxation, railways, water conservancy and other departments, and at the provincial, municipal and national levels, there is basically a mainstream school preference. There will be different changes in different periods of the top leaders' rule, but it is real.

Such a top-ranked clinical trial center in the country and is currently the only clinical trial center located in Hedong University. All the enterprises and institutions related to biology, zoology and pharmacy in the country will definitely pay more attention to Hedong University when selecting people this year.

Even if the hospital, health bureau and other systems are selected, they will look up to the students of Hedong University at a glance.

The so-called intoxication, which is smoked from vinegar and which is smoked from Nobel Prize winners, should be treated differently.

For students of Hedong University, a building of the School of Science is really not that charming.

Not to mention, construction is being stepped up next to it and a new building is being built.

The excitement of students and faculty can also be proved from another perspective that everyone is actively applying to join the clinical experiment.

It’s not for the subsidy of 20 cents a meal a few days - the most taboo thing in clinical experiments is to use money to seduce people to participate in the experiment, which is different from the idea of ​​ordinary people.

That is, for the first phase of clinical experiments, the subsidies are given a little more because healthy people need to do safety tests, but it is just a little more, which is far from enough to attract people to actively participate. European and American pharmaceutical companies will give some medical insurance in disguise, which will have a certain attraction to low-income groups. However, the gray area ends here. Going forward, it is basically illegal. Once discovered, the experimental results will be highly suspected.

However, the students and faculty at Hedong University are not due to subsidies and non-existent medical insurance. Their enthusiasm, ultimately, can be attributed to dedication.

Or, it is a heroic complex.

In this era, heroes are still the pursuit of most people, at least, the deep pursuit of most people.

The students and faculty members in the ivory tower have even more traditions.

The experiment was repeated in the first phase, so it was also done quite smoothly.

It originally only requires dozens of people to participate. The core of its focus is safety and pharmacokinetics. In short, it means excreting something and whether it will generate additional toxicity in the body. The most troublesome thing is to recruit volunteers, analyze things, and pull a few skilled experimental dogs to do it. Not to mention that Pfizer has completed a phase of clinical experiments.

Yang Rui did the repeated experiment mainly to verify it so that Pfizer would not intentionally deceive and buy fakes by himself.

Getting a good start and getting familiar with the equipment is one of the effects, and it does not even need to follow the steps of the first phase to complete it. In any country, you do not need to do two clinical phases. Do it all in one thing, and it will be a waste of millions.

After a very short process, the highly anticipated second phase clinical trial was put on the table.

This time, the building of the Clinical Experiment Center was fully utilized.

The focus of the second phase clinical experiment is divided into two items. The first focus is still safety. What you need to do in the first phase is not only to do in the second phase, but also to expand the scale.

The second focus is efficacy.

From the screening of compounds to animal experiments, to the first phase clinical trials, and then to the second phase clinical trials, the previous part is also concerned with the efficacy, but no experiments have been conducted on the human body. Now, it is finally time to test and obtain them.

Huang Mao came from Huarui Laboratory specifically for this purpose and was responsible for the coordination of all experimental work.

Tu Xian and his wife Wang Xiaoyun also went to Pingjiang to help. Sildenafil bought medicines in the name of Yang Rui, and their rights and debts belong to Yang Rui. Naturally, he could not let the ion channel laboratory or Yang Rui genetic engineer come to help. In fact, it would be fine to go to them to help, but Yang Rui felt it was unnecessary.

What is most needed in a clinical experimental center is doctors. It does not even require a permanent research team. Whoever wants to test drugs will rent the experimental center. Changing a research team will not affect the accuracy of the experiment.

Of course, to be on the safe side, the newly built Hedong University Clinical Experimental Center still needs a permanent team. Yang Rui entrusted Li Zhang Town to hire several doctors and recruit several pharmacokinetics scholars himself, even if he formed the research team of the Clinical Experimental Center.

That is, he is now famous, otherwise investors would be furious when they see him doing things like this.

I only organized the research team after spending all the money, but I was so casual.

The other is because Yang Rui showed insufficient confidence.

If you lack confidence, don’t buy sildenafil. How expensive is this thing?

It’s really a puppy who sells his land and doesn’t feel sorry for him.

The bank cadres of the four major banks are so distressed that they are so distressed.

Yang Rui still directed everyone to do things with a plain attitude.

It was said that it was a commander, but it was actually a discussion.

He has never conducted clinical trials before. Instead, several pharmacokinetics scholars, at least have experience in developing Chinese patent medicines. Combined with some public information, they have learned it well.

The difficulty of clinical trials is fundamentally the case.

There were many clinical trial centers in Africa in later generations, such as Uganda, and how many qualified doctors could there be?

People still make antimalarial drugs, HIV drugs, etc.

However, this is too ridiculous in the eyes of the bankers.

The vice president who came to inspect heard about Yang Rui's reputation and was reluctant to offend him easily, so he directed his manager to ask.

"What are the standards for phase II clinical trials?"

“What do you expect its bucking capability will be like?”

"How sure are we to pass the second phase clinical trial?"

The manager has many questions, but not many people can get Yang Rui's answers.

Several vice presidents of the bank had to stare at the snow-white ward and the conference room day by day, and in a daze.

They can't understand the things on the blackboard.

They still can't understand what's in the ward.

It’s useless to understand it, or it’s just a matter of increasing worries.

After discussing after dinner, several people basically made it clear that Yang Rui was suspected of cheating money, but they were still unpredictable why he did this.

"Professor Yang, what's the result today?" It was another dusk. Wang Xiaoshu from ICBC followed Yang Rui out, exhausted.

"Oh, the results today are not very good." Yang Rui smiled slightly and showed it to people who don't know, just thinking that he was calm and had super stress resistance.

Wang Xiaoshu was not in the mood to laugh today. He smiled blankly and said, "The result is still bad, are you not in a hurry? Yes, the expenses of hundreds of millions of dollars are not your money."

"Why is it not my money?" Yang Rui was displeased and said, "What your bank took out is a loan, but it was not given to me. Why? Do you want to erase my debt?"

"I guess this is it!" Wang Xiaoshu jumped up all of a sudden, not as flexible as a 60-year-old cadre, shouting, "You want to use our money to do medical development. You are too cruel. Do you know what the concept of 180 million US dollars? That is how much hard-earned money from ordinary people, you just snatched it away... I, I am also a person who is about to retire. I am not afraid of you. I want to report to the higher authorities and stop this matter!"

"Stop?" Yang Rui shook his head and said, "Don't joke, you are just a bank that pays the money. Pharmaceutical development is not your major."

"Pfizer is always professional. I don't believe that Pfizer didn't do the second phase of clinical practice. They must have secretly done the second phase and sold it to you because they didn't perform well. I don't understand pharmaceutical development, but I know how to buy and deal. Is it so easy for a fool to sell medicine to you like this? Can a big deal worth hundreds of millions of dollars be so casual? That is, you young people dare to do it like this."

What Wang Xiaoshu said made Yang Rui look at him with admiration.

It is very clear that it is possible that Pfizer had secretly performed the second phase of clinical practice.

Unlike many Chinese people nowadays, they think foreigners are very abide by the rules.

Pharmaceutical companies are good at doing life business, so follow your sister's rules.

It is indeed difficult to do clinical experiments secretly, but it does not mean that it cannot be done.

Pfizer does not really not conduct clinical phase II publicly, but it is still very likely to conduct a small-scale efficacy study in private.

Of course, such small-scale tests often cannot fully grasp the situation of drugs, and omissions are likely to occur. However, Pfizer used expensive contracts to make up for the omissions.

Therefore, although Yang Rui didn't know whether Pfizer had a second phase of clinical practice, Wang Xiaoshu's guess was very reasonable.

It is very likely that Pfizer decided to sell sildenafil to Yang Rui because he did not see the best results in a small-scale test.

At least, they did some tests and judgments before selling.

In terms of the pressure reduction effect alone, Pfizer has already made a lot of reasons for selling sildenafil.

Wang Xiaoshu's guess is also very reasonable.

Unfortunately, he does not have the right to decide.

Yang Rui said: "I can't explain to you about scientific research. You obviously don't know much about the field of medicine. In short, it's your business. I don't care whether you believe it or not, but I'm not polite if you influence my research."

"It's useless to be polite to me. I know you are the dignified Professor Yang, but I tell you that the four banks invested in have already agreed. If you don't give a reasonable explanation, we will freeze your money if necessary." Wang Xiaoshu seemed to be aggressive, but in fact he was still very guilty. If he had to say that his level was already very high, let alone a small research institute, even a state-owned enterprise would not dare to underestimate him.

But while speaking, Comrade Wang Xiaoshu still gave enough retreat. While winning over the other three banks, he also explained the necessary situations...

But Yang Rui looked behind him, shook his head, and said, "Where are the representatives of the other three banks?"

"I'm fine." Wang Xiaoshu was also a little embarrassed. Among the four people, he was the oldest, closest to retirement, and had the strongest sense of justice. The attitudes of others should be said to be unparalleled. He agreed behind his back, and he was still uncertain about what he was doing in person.

Yang Rui guessed the reason and smiled disdainfully, "I'll say that."

"I'll listen." Wang Xiaoshu focused.

Yang Rui said "hmm" and raised his voice slightly to ensure that there are people hiding around him. You can also hear it: "Which bank is the first to cause trouble, which bank's debt will be paid in the end. Have you heard it clearly?"

Regardless of whether it is 180 million or 580 million US dollars, the four banks all contributed proportionally, but when it comes to repayment, can they pay back hundreds of millions of dollars in one go?

Of course it is impossible. Even if you sell the new drug in one go, the other party may pay in batches, and maybe they will use shares to deduct cash or something. Not to mention sales reimbursement, they always have to be repaid one after another.

If you can't sell it, it's even more than a mess. If you don't have enough money to repay, who will give it to first and who will give it to?

If executed according to the law, debt repayment will be carried out in order.

However, no matter how strict the law is, there is room for activity, not to mention that this is the non-standard debt of the four major banks and Yang Rui.

When it comes to paying money, Yang Rui does not give money according to proportion, or returns the money in order, so who can do what?

Wang Xiaoshu seemed to have been hit in the chest by a heavy hammer, and his blood pressure instantly rose.

"Okay, go back and have a good rest for a day. I will take you to see the specific situation tomorrow so that you can understand more about clinical experiments." Yang Rui was also afraid of angering the old cadre to death, so he smiled and eased the scene and gave Wang Xiaoshu a step.

"I want to bring an expert." Wang Xiaoshu blushed and took the opportunity to make a request.
Chapter completed!