"The price of sildenafil in North America is US$7. If we take out the cost, we can get about five yuan of gross profit per pill. This is mainly because Green Stone Corner bears a lot of the early costs. If they want to get the global sales agent of sildenafil, they are willing to bear more..." Yang Rui held the report in his hand, and did not open it, but introduced it to Director Hu like a retelling.

Director Hu is the director of the Chemical Pharmaceutical Revitalization Office and is considered a supervisory unit of Huarui.

Of course, Yang Rui can also report to the Ministry of Health's Drug Administration and other departments, but that is unnecessary and people are embarrassed to listen.

Director Hu listened very seriously.

What exactly happened to new drugs? Before Yang Rui, there was really no experience in China.

Although the country approves so many drugs every year, except for generic drugs, the rest are Chinese patent medicines. Chinese patent medicines can only make money in China, and what they earn is the most boring money.

In the 1960s and 1970s, countries also exported Chinese patent medicines to Southeast Asia, Hong Kong and Macao, but there were very few since the 1980s. The main reason can be said to be the influence of many cultural factors, and the inevitable influence of the FDA.

Before the FDA, the quality of medicines in Europe and the United States was not very good. People who were not often eaten by death but disabled people often had them. There were not many diseases that could be treated. Many common diseases were powerless, especially terminal illnesses such as cancer. Taking Western medicine and Chinese medicine, the survival time was similar, and they basically depended on their personal constitution and spirit.

But after the 1980s, the level of Western medicine in common diseases has obviously reached a higher level. From a scientific research perspective, it is a generation of scholars who grew up after World War II, especially those who grew up in the genetics era, who studied the biological technology, which finally began to be applied to the field of people's livelihood. For example, although the cancer conquering plan that Dalbeko in the 1970s was declared a failure, the 1 billion US dollar was not a pure waste. The research results generated by this money were finally released one after another in the 1980s and 1990s.

With such a scientific research foundation, the strong Western politics have room for development.

By around 1990, Southeast Asian countries had established corresponding drug review mechanisms, and the previous play of traditional Chinese medicine was not easy to achieve.

For leaders like Hu Chi, he hates and is afraid of words like FDA and Western medicine.

This feeling is a bit like Chinese football facing the five major leagues and the World Cup. On the one hand, he was eager to enter the game, and on the other hand, the key to the decision to enter the game is not himself. In addition to trying hard to understand the situation and issue some useless orders, the rest is to promote the origin of football from Cuju. During the Song Dynasty, there were Cuju masters who entered the road with the ball and went straight to the sky...

Sildenafil passed the FDA review, which is equivalent to a player entering the Premier League giants. If he sells well, he will become famous. Hu Chi naturally wants to understand the details.

He wanted to know, so Yang Rui introduced it.

He first talked about the review process of the third and fourth phases of clinical practice, and then talked about the later negotiations with Pfizer, then talked about the contract and sales policies of Green Stone Corner, followed by the performance of sildenafil in the market and several models of recovering funds.

Hu Chi was confused when he heard it.

Chinese people in 1990 know too little about foreign countries. Even pseudo-high-level officials like Hu Chi don’t understand the professional situation in the field of medicine.

After listening for a while, Hu Chi finally gave up and decided to start with what he understood. He smiled and said, "It seems that you still made a profit, hahahaha..."

"Earning is profitable. Speaking of this, I want to talk about where the funds go." Yang Rui also expressed his goal for this trip.

Hu Chi nodded repeatedly: "The funds have to be spent to be valuable, you said."

"Peking University Ion Channel Laboratory has prepared to participate in the genome project. The instruments, equipment, personnel and training have been completed. Can you please come forward and urge negotiations?" The human genome project is an international cooperation, that is, a plan between countries, so it needs to be negotiated based on the state. Of course, Yang Rui had already completed the preliminary communication, and there was not much professional part left, and the rest were all political and diplomatic work.

However, political and diplomacy is also the most complex part. In the context of international cooperation and confrontation, no one knows whether they will become a bargaining chip for exchange.

The international situation in 1990 is very unfriendly to China, and is a world of difference from the mid-1980s.

When Yang Rui won the Nobel Prize, the media would like to support it everywhere. There was even a voice within the Nobel Prize Committee, hoping to give China a Nobel Prize and promote the development of China's democratic cause from the side...

But after 90 years, the media's voice changed completely, and everything in China would become a mistake.

Yang Rui's cloning of sheep is almost regarded as a threat...

This is the political correctness of the Western world and what various committees care about the most.

If it weren't for the fact that the pharmaceutical companies were really strong, the pharmaceutical system was really rich, and the lobby groups were really powerful, and the verbal people really needed to use it, the passage of sildenafil would be subject to various restrictions.

Therefore, Yang Rui did not have a very relaxed and casual attitude towards joining the Human Genome Project.

Hu Chi also knew the difficulties of this matter and pondered: "You also know the current diplomatic situation, and I can only say that I am doing my best."

"Well..." Yang Rui stroked his chin and said, "If necessary, our Peking University can provide some help, such as funds and personnel."

With his current influence, it is OK to represent Peking University.

As long as projects like the Human Genome Project are won, Peking University's influence will greatly increase, which is a great thing that both sides hope for.

Hu Chi didn't expect Yang Rui to say this, and couldn't help but smile: "Just sildenafil, they should help."

"It's better to give it something real." Yang Rui gave money openly. Green Stone Corner lobbies in the United States, spending tens of millions of dollars, tens of thousands or even tens of thousands of dollars in cocktail parties, seven or eight sessions at one time, and it's enough to hold 800 redeems in China. It's been three and a half years since it was returned home in glory.

Units like the Ministry of Foreign Affairs are very happy for employees of the ministry. Even if they don’t have any gray income, save some travel expenses, and buy some foreign specialties, they can make a fortune. However, for the unit itself, they have to use foreign exchange for the cost of every business trip, which is really not a good idea.

There are actually units like police station criminal police teams. Although employees are very comfortable on weekdays, when it comes to handling cases, they often drive thousands of miles to collect evidence and spend on food and accommodation for a long time on site, which is not a small amount.

It was because Yang Rui knew this that he often donated money to the police department in his jurisdiction. By the same token, he didn't care about donating money to the foreign affairs department.

If it is not considered a plug-in, if you analyze the difference between him and his scholars of his time, besides being handsome, he mainly has money.

If you have to analyze it carefully, it means you are rich and generous.

Even if other domestic scholars receive large sums of funds, most of them will use them carefully because of their past experience. This is an era when everyone regards frugality as virtue.

Yang Rui has no such habit. When scientific research reaches its peak, it is actually krypton gold.

Any advanced skill needs to be improved by spending several times, dozens or even hundreds of times more money.

In 1990, China was still used to following research. Simply put, it was used to following big guys. It was not as conscious as to enter the world by itself. When spending money, it naturally liked to consider cost-effectiveness.

However, being a server first has never been cost-effective.

Although Hu Chi was not used to such straightforward operations, seeing Yang Rui insisting, he agreed and turned around and said, "In this way, you have to consider the issue of domestic competition."

This is his intention to mention Yang Rui.

Yang Rui was not the Chu brother of the past, so he asked with a smile: "Have you heard any rumors?"

"You know my current location, there are always people who will come to test it." Hu Chi explained first, and then said: "People who pick peaches are always indispensable."

"Do you think they can pick them?" Yang Rui asked slightly and seriously.

Looking at the country, Yang Rui is not the only one who is calling for the human genome project.

Although Yang Rui shouted at the human genome plan from time to time, or even went to the Nobel Prize scene, when the national team decided the order, it was never judged by the size and number of sounds.

It is reasonable to say that people can raise the scholar who was the first to call the human genome project, or the oldest qualifications, or to bring a member of the school department to lead the way.

The Nobel Prize is just a prize, not a qualification, but a member of the school department is.

Moreover, for example, Professor Cai, Wu Hongbo, and Academician Zhu, their international reputation cannot be compared with Yang Rui, but their domestic reputation is not weak at all.

At that time, the Human Genome Project will be established, and it will not be impossible to give Yang Rui a deputy team leader and then hang the team leader up high.

Of course, Hu Chi supported Yang Rui, so he specifically reminded him and said: "If you pay attention, there should be no problem, but you must not ignore it."

Speaking of this, Hu Chi said: "You have attended more meetings recently and I will give you a reminder. In addition, you can also mention the human genome plan and create a preparatory group."

Yang Rui said a little boredly: "How can I have time to do so much useless..."

The preparatory team is just queueing up to eat fruit fruits, and they have to settle the others. Everyone is happy and they won’t be able to snatch them.

It is equivalent to making a promise to everyone and then protecting their own high position.

But Yang Rui was not very willing to do so.

The seat ranking is not as easy as imagined, nor is it his expertise. The most important thing is that the human genome project is to really do things. At that time, who will work in a group of old men in their seventies and eighties?

Hu Chi asked: "What do you have to do recently?"

Yang Rui pointed and said, "I want to go to class. Huarui also has to consider developing new drugs. The Ion Channel Laboratory and Huarui Laboratory have regular research. In addition, I plan to build a medicine valley."

"Medicine Valley?"

"Concentrate some pharmaceutical-related enterprises, just like development zones, but Huarui privately does not pursue short-term benefits, nor does the development zone take care of this and that. It just focuses on industrial concentration and concentrates some enterprises. In addition, we provide supporting housing for enterprises, only renting but not selling, reducing their worries." Yang Rui paused and said, "The loan amount provided by the Bank of China is almost 10 billion, so we have to use it."

“Is it big?”

"Now it occupies a large area of ​​Pudong, and Shenzhen also gives a large piece of land. It can accommodate about a few hundred companies and still have the allowance." Yang Rui stopped and said lightly: "The company is responsible for the construction of the factory itself. However, in order to attract pharmaceutical factories, we have to undertake a large amount of residential construction. At present, it is estimated that at least 500,000 workers must be able to accommodate the subsequent ones, which is 1 million apartments. The amount given by the Bank of China is just right."

Hu Chi's eyes were all twitching: "Don't you have to pay back the loan?"

"There is still a follow-up profit, but isn't there a rent? If you pay it from each unit, you can get a lot less trouble."

"But...1 million sets?"

"Build it slowly, don't worry. The loans provided by the Bank of China are not unconditional, and they are willing to invest in infrastructure. If they are all used to make new medicines and buy machinery and equipment, they will be uneasy."

"That's the case, but your plan is really big."

Yang Rui laughed and said, "I originally proposed an idea, but the governments of the two places were too active. They sold land at a low price and were subsidized by policy. There was no way to make a fuss, so they became bigger and bigger."

"Then you have to be careful, don't make up for the gap at that time."

"Bank of China's loans were issued proportional to our US dollars, and the risk was not very high." Yang Rui smiled silly, feeling somewhat guilty.

How much will the 1 million apartments in Shanghai and Shenzhen be worth in 20 or even 30 years? Yang Rui himself is a little afraid to calculate it. He can only say that Huarui will develop new drugs in the future, and rent will be enough.

There are many state-owned enterprises that rely on rent to survive, but they are not inferior to one private enterprise.

For Yang Rui, Yaogu is really trying to solve the current problems.

Bank of China has to spend loans, and it cannot be spent in places that are too risky, otherwise people will also interfere. In this case, infrastructure investment is the best choice. On the other hand, Huarui does need to have a concentrated industrial base in big cities. With the hot sale of sildenafil, Huarui's sales network across the country has been greatly enhanced, and the brand has gradually become louder. At this time, we cannot only look at the development of high-end new drugs.

With China's industrial scale and consumer market, once it is involved in the production of various generic drugs, the industrial park with hundreds of thousands of workers cannot be ahead of schedule.

As for 1 million houses, in this context, it only increases Yang Rui's personal satisfaction - everyone knows that the house is going to fly, so there is no reason not to buy two more houses.

To this end, Yang Rui also asked to build the house as large as possible on the grounds of providing high-standard housing.

Hu Chi could not guess Yang Rui’s idea. After a change of thought, he returned to the previous topic and said, “Since you want to build a medicine valley, it’s better to do this. I have promulgated the GMP standards you made in advance in the name of the Chemical Medicine Revitalization Office.”

“Issued now?”

"The policies and regulations are all prepared. If they are implemented on January 1 next year, the review will be started this year. This matter has always been promoted by you. You have to take the time to understand the situation of various pharmaceutical companies, so you can arrest it. How about the existing GMP committee and another committee is divided into? "Hu Chi said it for granted and expressed full respect to Yang Rui.

Yang Rui was surprised and saw the murderous intent.

The GMP standard mentioned by Hu Chi is a hard standard for pharmaceutical companies. If it cannot be passed, the result will be shut down and transfer.

As a designer of the standards, Yang Rui is well aware of the difficulties of standards. In history, more than 4,000 pharmaceutical companies in China have won the last 2,000, including the newly built ones, which means half of them are facing the crisis of being abandoned or closed down.

The committee responsible for standard review and its person in charge are equivalent to holding the power of life and death of all pharmaceutical companies across the country.

In this full-scale audit, even a well-known company may be eliminated due to some shortcomings. Yang Rui looked at Hu Chi and did not speak for a while. Such a major decision must not be something that suddenly came to mind.
Chapter completed!