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Chapter 414: Unintentionally planting willows

"What happened?" Everyone in the laboratory naturally gathered together.

Huang Mao turned an electronic screen on the experimental bench and said, "I saw a significant potassium electron flow before, and I just confirmed that it was detected again. Look at the record. The average single conductance is more than 20 pixie per meter, which is ten times larger than the single channel conductance of ordinary potassium ion channels."

Pixi is a unit of conductivity and one of the single-channel inspection marks. Ten times the conductivity is definitely abnormal, and everyone immediately gathers around to look at the recording paper.

Yang Rui looked at it for a while and realized what was going on.

This seems to be a feature of family gene encoding.

Yang Rui quickly searched in his mind and found four members of the family, and then he was a little amused and blew up.

Huang Mao found the first member channel of the family.

This is two different things from the aaa channel that Yang Rui imagines.

The Taa channel is the first identified potassium ion channel in history and the first identified potassium ion channel through gene cloning. There are quite a few papers describing it, and it is relatively simple to do.

Yang Rui originally considered that he first made a AA channel and easily added something to form a standard paper.

Even copying a paragraph of the paper on the aaa channel that would actually be published in 1987 may be published in "Nature".

However, scientific research is sometimes so caught off guard.

It is not something you can do whatever you want.

Historically, most scientific research results, especially breakthrough scientific research results, were unexpected surprises, and many times, even the result of making mistakes.

Although the Taa gene is the first potassium ion channel to be discovered, it is true that it was discovered by people who did not know what they would find back then.

Just like Huang Mao now, although he mutagenerated the genes of fruit fly, he didn't know which gene he would mutagenerate, or he was not sure if he could find it after mutagenesis.

After two or three months of experiments, Huang Mao has not observed uncontrolled shaking of fruit fly calves like scientists back then. On the contrary, Huang Mao found a phenomenon that is not easy to observe: the increase in conductivity.

Of course, the so-called difficulty in observing is also relative.

The Taa gene is also called the leg shaker gene. If there is a problem with this gene, the voltage of the potassium ion channel of the fruit fly will also be problematic. In this way, when the fruit fly is confused by ether, the calves will keep shaking.

But there are so many people in Huarui Laboratory who have done hundreds or thousands of groups of mutagenesis, or have not mutagenesis to the leg shake gene, or mutagenesis to the mutagenesis. At that time, there was no devastating fruit flies, so this phenomenon was not observed - this is also normal. If the phenomenon of gene mutation is so easy to observe, the biological world would not have played fruit flies for decades, and they were still playing fruit flies in the 21st century...

In terms of the unluckyness of the ethnic group, fruit flies have been more bad for eight lifetimes than mice.

In comparison, the aaa gene is easy to observe externally, while the increase in conductance observed by Huang Mao is the most easily observed phenomenon on instruments.

Because what you are doing is the potassium ion channel, it is appropriate to observe the conductivity of potassium ion, and the channel is even more special. The performance of its genes is 10 times the conductivity increase.

In this way, even if the accuracy of the instrument is not high, a change of order of magnitude is still easy to be noticed.

"Show me the experimental records." Yang Rui was still a little excited. The key to determining the potassium ion channel through the mutant gene is to confirm the appearance of the mutant gene.

If described in words, this is a very simple process: inducing gene A mutation and discovering that the organism has changed B, it is natural to determine that the function of gene AR spoon is to keep B from changing.

For example, if the aaa gene mutation, the fruit fly's legs tremble, so it is determined that the function of the aaa gene is to prevent the fruit fly's legs from trembling.

To achieve this, it is actually a very good paper, but it may not necessarily be included in "Nature".

To be sure to go to "Nature", you have to repeat the induction process constantly, and then determine why your legs are shaking and your legs are not shaking. It is ultimately a problem of voltage. Adding a smooth article, this is basically a good paper in "Nature". Of course, if you want to go to "Science", regardless of the content, the writing must be a bit literary...

As a literary scholar in the natural science community, the hairline forced by Science can circle the earth for seven and a half weeks together

Huang Mao was also excited and quickly found several boxes from the top cabinet, then took out the experimental records and handed them to Yang Rui.

His experimental records are very detailed, which is also Yang Rui’s requirement, or experience.

Twenty years later, foreign laboratories have recorded video experiments, with the purpose of recording the experiments in detail.

People who have just finished the experiment will have a very clear memory of the experiment process, but after a few weeks, months, or years, the memory will fade very well.

In the end, the institute with a good memory may remember the main or secondary steps of the experiment, but which instrument is used in the experiment? Which chemical reagent is used in the experiment? 100 out of 100 people can't remember it.

There is nothing to do with these details, but there will be more of them in the whole experiment. If it is a long-term experiment that lasts for several years, re-verify or re-compare, is it possible to do the experiment again?

Just do it again, the chemical reagents provided by different companies are also different, but the result is a deviation, so who is it?

In the experiment of potassium channel, Yang Rui had to first determine that if there was an abnormal conductivity, the experimental conditions did not change greatly.

Fortunately, the conductance of the channel changes very drastically, and the 10-fold change is basically difficult to affect the outside world, which makes the review work relatively easy.

When Yang Rui reviewed from beginning to end, Tu Xian and others had already begun to congratulate Huang Mao.

Huang Mao himself was a little worried about gains and losses. While looking at Yang Rui's unchanging expression with fear, he smiled and said, "Look at your red eyes, is the second author jealous?"

"Who is jealous of you? Our old Tu has also achieved results recently, right?" Wang Xiaoyun has the advantage of being a woman and can speak as much as possible.

Huang Mao laughed deliberately, replaced it with a proud expression, and said: "The first article of the Potassium Channel paper can take advantage of it, but the second article may not be necessary."

"As far as your current research progress is concerned, it is not certain whether you can do the first article, right?" Wang Xiaoyun poked her husband.

"I just need to do the experiment. How about the paper? Yang Rui is responsible." Tu Xian ignored his wife's competitive attitude.

Wang Xiaoyun punched him helplessly and said, "I don't have the intention to be ambitious."

"I'm not motivated when doing experiments every day." Wei Zhenxue screamed strangely and said, "You two in-laws are working like this, and other children should go to elementary school.

Wang Xiaoyun's face suddenly turned red and she didn't dare to speak. They were both busy in the laboratory, so naturally they didn't have time to have children. This was a little different from the ordinary marriage in the 8th.

Tu Xian smiled instead and said, "Old Wei, can a bachelor have children alone?"

Wei Zhenxue's momentum was stagnant. After thinking for a long time, he came up with a weird way of counterattack and said, "Do you believe it or not, I'll do the test tube baby myself?"

With the level of Huarui Laboratory, there are really hardware conditions for doing IVF, and Wei Zhenxue also has the corresponding operating foundation.

However, this kind of second-handed speech was only possible with Wei Zhenxue.

Normal people should at least find a big-breasted beauty or something.

Tu Xian was stunned by Wei Zhenxue's unexpected answer. At this time, Wang Xiaoyun asked coldly: "Have you used the test tube that has been filled with mung bean soup?"

"Puff..." Sun Ruyue, who had been afraid to speak, couldn't help it anymore and laughed out loud.

Tu Xian and Huang Mao also kept coughing.

Wei Zhenxue looked as usual and said, "I told you that the test tube contains mung bean porridge, and the separated mung bean soup."
Chapter completed!
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