Guan Yuntian once asked Dr. Tong the same question, but Tong Wei's major is materials science. After all, he is not a medical professional. Guan Yuntian felt that his answer at that time was not professional enough. When I saw Deputy Director Huang today, Guan Yuntian wanted to hear it first.

Hear what this insider has to say.

Being able to raise such a question, Lao Huang believed that Guan Yuntian was completely prepared. As the leader of the industry competent department, he had some friendship with Guan Yuntian. When he saw that his subordinate units were willing to make a difference in the research and development of new drugs, Lao Huang came from the bottom of his heart.

He was happy, so he took Guan Yuntian's issue very seriously.

Seeing Lao Huang's serious look, Guan Yuntian quickly complimented: "Huang Bureau, you are both the leader of the province's pharmaceutical industry and an expert in this field. The answers I get from you must be the most accurate."

Of course Lao Huang liked hearing this, and his expression became relaxed, "First of all, let me state that the topics we cover here only include chemically synthesized drugs and biological products, and have nothing to do with proprietary Chinese medicines. In short, as far as chemically synthesized drugs are concerned,

The most cutting-edge research field is mainly to screen the ingredients that are effective in human diseases from the molecular structure of nature, and then dissect the molecular structure, and then use synthesis or semi-synthetic methods combined with biological fermentation to treat this kind of ingredients.

The ingredients are developed until they are brought to market. Of course, this process is accompanied by various safety tests.”

"It sounds like it's just a few words, but it should be a long process."

"Yes, this is the difficulty in developing new drugs."

"Comparatively speaking, what stage is China in in this regard?" Guan Yuntian said.

"To be honest, basically no one in China is doing this kind of work because everyone is copying drugs whose patents have expired. Didn't you just ask about the gap in drug research and development? This is a real gap."

"Huang Bureau, you are both an industry expert and an industry leader. From your perspective, what do you think is the reason for this gap?"

Lao Huang did not answer immediately. He thought for a while and then said: "In the final analysis, the first is funding, and the second is technology. Let's talk about funding first. Some organizations have done statistics. It is said that in the 1990s, foreign countries developed a

For new drugs, the investment in scientific research and development alone amounts to more than one billion U.S. dollars! You can imagine how expensive the research and development of new drugs is! But those large multinational pharmaceutical companies can afford this money, and they have been conducting research in this area all year round. In contrast, domestic

How much is the annual net profit of pharmaceutical companies, even the so-called major pharmaceutical groups? Even if they have such ideas, they cannot come up with that money, and the gap will naturally form."

"In addition to financial constraints, is there any gap in the country in terms of technology?"

"In my opinion, the technical constraints are even greater. In fact, if we really need to have good ideas, funding is not a big problem, because domestic venture capital has gradually increased, and good projects can be financed through financial institutions or other channels.

It’s not difficult, the key is the lack of technology, especially basic research, which makes it impossible to even start research on new drugs.”

"It seems that basic research is too important in the development of new drugs!" Guan Yuntian said.

"Yes, when I talked about screening molecular structures from nature that are effective for human diseases, the direction is certainly not wrong, but you first have to figure out which types of diseases a certain molecular structure is effective for? Then you also need to know roughly which plants can be obtained from it.

Or find compounds with this structure in animals, otherwise it will be like looking for a needle in a haystack, which will result in a lot of manpower, material and financial resources being spent, and ultimately nothing will be found. The above process cannot be carried out at all without the support of strong basic research in related disciplines." Lao Huang said.

"Director Huang, it is said that basic research results cannot be patented and generally have to be published publicly. Now that the Internet is so developed, domestic scientific researchers can also learn about the latest research progress in related fields from the Internet. Why can't we use other people's basic research results?

How about serving our new drug research and development?" Guan Yuntian's science background helps him understand this information.

"Heroes think alike. Your idea has also been thought of by some domestic scientific and technological personnel engaged in medical research and development. This idea can be regarded as a shortcut. On this basis, a very few domestic research and development institutions and scientific researchers have also made some achievements in the research and development of new drugs.

However, there are two factors that seriously hinder the implementation of this idea. On the one hand, many scientific and technical personnel either cannot understand foreign literature in the field of basic research at all, or have only a partial understanding of it. They do not know how to use what results can be used for their own purposes.

There are very few scientific and technical personnel who understand the true significance of those basic research results; on the other hand, developing new drugs requires large amounts of capital investment, which is also the biggest obstacle."

"Yeah, if you can't understand foreign literature, you can find someone to translate it. The basic theory is esoteric and difficult to understand, but you can gradually understand its meaning through study. These should not be difficult. The key is that developing new drugs requires a large amount of investment.

, this problem is not easy to solve." Guan Yuntian paused, "Well, isn't it said that domestic venture capital is also very popular? You can ask venture capital institutions for help!"

Lao Huang shook his head when he heard this, "Oh, how come you, such a big boss, make things look so simple? Institutions engaged in venture capital are all extremely smart, and they don't want to take any risks with you."

“What is risky investment without taking risks?”

"Those people are typical of those who don't let the hawk fall in love with you! Only when your research and development reaches a certain level and achieves certain results, and the value of the results is recognized by the authoritative department, will the venture capital institutions take a serious look at you. Otherwise, you will not be able to keep track of you."

They don't even have a chance to speak!" It seems that Huang has some knowledge of venture capital.

"Then start the research and development work first and show it to them. After achieving certain results, we can invite venture capital institutions to join." Guan Yuntian said.

"Your idea is good. The problem is that to carry out research and development work and to achieve certain results in the development of new drugs, it also requires a large amount of investment. Where does this fund come from? Most scientific research institutes simply cannot afford it.

!”

"It seems that things are indeed not as simple as imagined. Drug innovation faces many difficulties. It is indeed not easy to make a difference in this area. However, our difficulties at Changda Group lie in the first aspect. As for funds, it is not too big.

question."

"What you lack is talent. Well... you can recruit them!"

"Recruitment is one of the ways to solve the talent problem, but what we need are academic leaders. It is difficult to select the talents we need through general recruitment methods," said Guan Yuntian.

"Academic leaders are almost expert-level talents. It's really not easy to recruit. What are you going to do?"

"There is no plan! I am asking for your help."

"Me? You know we are just an industry authority and have no power to transfer personnel. I'm afraid I can't help you with this." Lao Huang spread his hands.

"Huang Bureau, this is not the era of planned economy. Even if you are the leader of the personnel department, you probably can't help, because the current employment mechanism is a two-way choice. Who you want to work in Changda Group is not sure yet.

I'm willing to go." Guan Yuntian said.

"That's right! You know I can't help you, so what's the point of looking for me?"

"Although you don't have the power to allocate personnel, you have information resources! We need the relevant information you have and then find people based on the information." Guan Yuntian told the truth.

"Oh, that's what you mean! So what kind of information do you need?" Lao Huang thought Guan Yuntian's recruitment plan was unique.

"Huang Bureau, you are both an administrative leader and an industry expert. You must have some knowledge of drug R&D institutions in the province and even the country. Which universities and scientific research institutions do you think are stronger in drug R&D?"

"Well..." Lao Huang stopped. He felt that this was something he needed to recognize.

If we were to treat the problem seriously, the information given should at least be accurate and reliable, so as not to mislead old friends. Therefore, it took him several minutes to tell him everything he knew about scientific research institutes and colleges and universities.

Guan Yuntian listened very carefully, interrupted from time to time and took notes.

"This is what I know about the industry. In fact, most of this information can be found online, but the content is not necessarily so specific." Huang finally said.

Guan Yuntian felt that it was quite rewarding, "Huang Bureau, thank you for the information you provided! You are right, a lot of the information found on the Internet is not accurate, a lot of information is out of date, and the information of some units has not been updated for several years.

.”

"The information I provided may not be comprehensive, but the situation I learned is basically accurate, because we have to meet with the leaders of these units at the annual national industry conference."

"That's why I want to consult with you in person. Otherwise, where would we get such accurate information? Bureau Huang, it's almost time to get off work at noon. Find a place and let's have lunch," Guan Yuntian said.

"You can't drink at noon. Let's get together later."

"This is the first time we have met since you were promoted. You have to give me a chance to congratulate you. In addition, I have some questions to ask you, and I hope Director Huang will not hesitate to enlighten me."

Unable to refuse the warm hospitality, Huang had no choice but to ask for leave from the bureau office, lying that he had guests at home and needed to go home at noon.

In a small private room of a high-end hotel, Guan Yuntian sat down with Lao Huang. After arranging the dishes, he asked the waiter to bring a bottle of Maotai. "Forgive it, we can't drink at noon!" Lao Huang declined.

"Drink less. We can have a bottle of wine for both of us. It won't delay anything."

"That's not okay. The unit has regulations. These are disciplines and no one can violate them."

"I heard you asked for leave from the office. This is your first meeting after your promotion. You have to drink some."

Lao Huang couldn't refuse, so he had to agree, "Okay, I won't drink too much."

After the food and wine were served, the two of them chatted while drinking, "Mr. Guan, why did you suddenly think of research and development of new drugs? I've never heard of you talking about it before."

"It's not a sudden thought. This is something we have wanted to do for many years. It's just that we haven't had the opportunity to mention it to you before. Our technology center not only does new drug research and development, but we also want to do pioneering research in the field of new materials.

.”

"Your ambitions are not small! You have to know that investment in scientific research is not like production, and the risk is very high. In many cases, the input-output ratio is very low, and there may even be only investment but no output. As a company, don't you have any concerns?

?”

“The risk issue has been considered for a long time, but we know better that a company without technological innovation capabilities, no matter how well it does at the time, has no vitality. In the fierce competition, it may be eliminated that day.

No matter what kind of product it makes, if the company itself does not have the ability to develop new products and new technologies, it will not only be unable to achieve continuous technological progress, it will be difficult to achieve a complete product chain, and it will be impossible to achieve the sustainability of the company just by introducing technology from the outside.

Sustainable development. Compared with the life and death of the enterprise, this risk is nothing." Guan Yuntian said.

"This is indeed true. You have calculated this account very clearly. According to the many companies I have contacted, almost no one in other units has thought of such a stake."

"Yes, people are very realistic. Many people are really reluctant to invest their hard-earned money in scientific research and development with huge risks. This is one of the main reasons why it is difficult for us to build a century-old enterprise in the manufacturing field, right?" Guan

Yuntian Dao.
Chapter completed!