Fan Lunding watched the carts of rats transported into Huarui Laboratory, his face was gloomy and clear.

Animal experiments are a great progress in the development of a new drug.

Most new drugs will fail in the synthesis stage after passing target screening. For example, if products such as Coenzyme Q10 are not directly obtained from animal tissues and enter the market at a high price of health products, there is no possibility of commercialization.

This is also because the efficacy of Coenzyme Q10 is not significant enough. If it can really treat heart disease rather than a small auxiliary effect, pharmaceutical companies in various countries have long taken out billions of dollars to try to synthesize it.

Although the synthesis of organic molecules is difficult, it is just a graduation thesis for a doctoral student.

Of course, some doctoral students cannot complete their graduation thesis anyway, and some people cannot graduate for five or six years.

In any case, entering animal experiments means that a large number of chemical molecules have been synthesized, and if they are sold now, they can already obtain considerable profits.

Fan Lunding thought of the possible bonus Yang Rui had won or the bonus Yang Rui lost, and was in a daze again.

"Does this Chinese know what he is doing?" Fan Lunding thought to himself that if he had the ability to synthesize more than 30 compounds a year, he would have had an annual salary of one million. No matter how he thought about it, he would not want to stay in a third world university.

Yang Rui synthesized so many compounds in less than two months, even if there is theoretical research - this is where Fan Lunding's dental acid is more effective. When did Yang Rui do theoretical research? Fan Lunding now knows that in the past more than a year, Yang Rui completed the semi-synthesis of Coenzyme Q10, the research on potassium ion channels and the invention of PCR, and then wrote a genomics book...

Fan Lunding had never imagined where Yang Rui's time for theoretical research came from.

Although many scholars have famous high-yield periods, such as the famous Miracle Year, this Latin word is used to call Newton's 1666. In that year, Newton left Cambridge and returned to his hometown to avoid the plague. In this year, to be precise, from 1665 to mid-1667, Newton constructed calculus, established the law of universal gravitation, and completed the experiment of decomposing visible light into monochromatic light, which is equivalent to reshaping the three fields of mathematics, mechanics and optics.

The Year of Miracle in English belongs to Einstein's 1905. In this year, Einstein founded the Special Theory of Relativity and published two papers in succession, "On the Electrodynamics of Dynamic Body" and "Is the Inertia of Objects related to the mass it contains?" In the same year, three other heavyweight papers brought Brownian motion and quantum theory to a new realm, either of which was Nobel Prize-level.

Compared with Newton's Year of Miracle and Einstein's Year of Miracle, Yang Rui's 1983, or 1983 to 1984, is not praised. Although PCR is strong, it is not as strong as calculus or quantum theory. Gravity and special relativity are immortal works, exceeding PCR by more than one order of magnitude.

However, these things are more than one order of magnitude for Van Lunding.

Standing with Van Lunding, watching the car carrying mice enter and exit Frankie and Arnold.

When the two heard Fan Lunding's words, they looked at each other and thought to themselves that Yang Rui knew what he was doing.

Frank's butt had been tilted long ago, so he was too lazy to say more. Arnold felt that Van Luntin was of value and comforted him: "No matter what Yang Rui thought, we can achieve our goal."

Fan Lunding smiled bitterly: "I thought that making 20 active substances can drag down Huarui's experiment..."

If a small biological company can produce 20 backup targeted active substances in three years, it will be lucky.

Time is also a very large cost for a biological company, and it also implies the problem of success rate. Simply put, the cost of the results achieved in three years is basically more than three times the results achieved in one year.

If Yang Rui spent three years to produce 20 active substances, the materials and manpower consumed during the period would naturally be needed to do experiments every day for three years.

However, he has now spent two months producing 20 active substances. He has made every effort and can't spend much material, so how can he achieve his goal?

Arnold originally hoped that Yang Rui would sell the catalyst formula of Coenzyme Q10 because of his continuous increase in scientific research budget. The result was just the opposite. Yang Rui could completely lower the scientific research budget and make his plan almost bankrupt.

Arnold wiped his face and said, "They are now going to do animal experiments on more than 30 compounds at the same time, which will also increase the immediate cost. You can first stare at them and see the results before deciding what to do, and don't be discouraged."

"Gris joined Huarui Laboratory. They did animal experiments and the possibility of achieving results was very high." Van Lunding backed.

"You have to continue to play your role and strengthen guidance, for example, try to improve their standards. Animal experiments are also very expensive, and the results will only be announced sooner." Arnold kept cheering Van Lunding.

Frankie said casually: "Yang Rui is a young man in the pharmaceutical field, but you don't listen to whatever you say. Don't raise the standard too outrageously, so as not to return you."

Van Lunding nodded silently and said, "There is no need to make any special improvement. I will directly translate the FDA's request to him. Such a team will never pass the test."

The FDA has always been evaluated by too strict standards in the industry. The same medicine can be marketed in Europe but often cannot be marketed in the United States.

By the 21st century, this polarization situation has become so serious that Europe has more than 200 new drugs than the United States, so bringing good European drugs back to the United States has become a business.

Whoever can buy the US operating rights of a European drug and then pass it through FDA animal experiments and phase III clinical trials often means hundreds of millions of dollars in revenue.

Therefore, it is a very high requirement to take the requirements of the US FDA as a standard during the development stage.

Half of the drugs will lose their qualifications to market as a result - Europeans will not want you failed products under the FDA standard, they want successful products that can pass their own standards.

Van Lunding received Arnold's clear instructions, but he didn't see the guinea pigs entering the cage, and immediately returned and picked up the rules.

On the other hand, a large number of teenage mice and rats were locked in a compound not far away.

Yang Rui's Huarui Laboratory originally had a large amount of free land, and in order to avoid being taken back by the government, yards were built one after another.

The yard where mice and rats are detained has been designed long ago, and experimental animals are also an indispensable configuration for biological laboratories.

Yang Rui even designed a location to detain gorillas in advance.

However, the ones that are available now are guinea pigs and rats.

The white mice are cuteer. They are bred from small house mice. As the smallest mammal, the white mice have been studied most thoroughly and are the most convenient for primary experiments.

The rat is a white rat, which has multiple breeds, including the Chinese brown rat, that is, ordinary house rats, which are relatively less cute.

But whether it is cute or not, these guinea pigs and giant mice have to contribute to the development of human medicine and biology.

To be honest, this is a very cruel act, but reality is so cruel.

Animal experiments for cosmetics are most susceptible to criticism from society, especially animal organizations, so many people initiate activities that do not use cosmetics or "free from cruelty". However, even if a girl who loves beauty can refuse nail polish for safety tests with beautiful white rabbits, she can refuse sun protection concealer isolation hydrating body lotion baby oil day cream night cream mask aftershave water removal cream - patients with cancer, AIDS, diabetes Parkinson's burns, but they cannot refuse to save their own medicine.

The only thing that can be done is to ensure the necessity of using experimental animals and to ensure the living environment of experimental animals.

Grace carefully checked each breeding cage, and while hanging labels for each cage, she carefully fed a small amount of water to the mice and the mice, and asked about various indicators in simple English.

Wei Zhenxue graduated from the Department of Chemistry. He had never done animal experiments before. He was a little afraid of mice. He looked at him from a distance and said sarcastic words: "If my wife is so kind to me, I would be willing to be a guinea pig."

"Write these words down and wait a few days before we can read them." Wang Xiaoyun laughed twice and stepped forward to help.

Wei Zhenxue looked at the two ladies' working conditions in detail and said a rare good thing: "Old Tu is lucky. If you want to marry a wife, you have to marry a good wife and a good mother."

Tu Xian twitched the corners of his mouth twice, shrank his neck, patted Wei Zhenxue's shoulder with deep emotion, and said, "If a biological woman treats you well, you have to think about her deep purpose."
Chapter completed!