When Yang Rui described to Professor Jiang and Academician Zhu, he was underestimated, but in fact, he knew that using rhodopsin from cow as G protein-coupled receptors was at least three CNS papers away from the current mainstream scientific research direction.

The first top paper is to sequence the adrenergic genes; the second is to sequence the rhodopsin of cattle; the third is to discover the amino acid sequences of the adrenergic gene and the G protein-coupled receptor, which are highly similar.

This whole process actually has a certain probability.

What if Kobierka did not do the adrenal glands could be sequenced? What if no one happened to sequence the rhodopsin of the cow? What if no one was idle and compared the amino acid sequences of the two?

This is actually an amateur problem.

These three probabilities are like asking, what if no one captures the hills ahead in the siege battle with heavy troops, what if it is not just destroyed the enemy's heavy artillery group, what if it is not the time that happened to be consistent...

G protein-coupled receptors are used to fight meat grinding, and there is not that much. Why, Kobeerka did not do the adrenal glands that can be sequenced by genes? It won’t take long to do it.

Maybe it will be one or two years later, but not too long.

What should I do if no one goes to sequencing the rhodopsin of a cow? It’s like asking what to do if the three hours of artillery fire is not enough. If not enough, blow it up for another three hours!

So many laboratories spent so much money, and they were all in vain and didn't even have a name left. It was just a laboratory where adrenaline-energic genes and bovine rhodopsin was chosen and achieved results.

With more soldiers charging, there are always those who survive. It is not that the enemy's machine guns are sweeping slowly, nor that you have special skills in hiding guns, but that there are enough people who block the gun holes on your own and your dog is alive.

Of course, Yang Rui is not prepared to be cannon fodder.

That's why he sacrificed the ox rhodopsin protein.

This is a secret that Europe and the United States have only discovered for a while.

It is just a scholar who reads literature faster, and it is probably only seen.

If Yang Rui had not been looking for it in a targeted manner, he would probably not have been able to see this information in a year or two.

In one or two years, other scientific research projects have become very nervous. In terms of G protein-coupled receptors, it is almost equivalent to giving up completely.

This is also a part of the difficulty of scientific research by scholars in third world countries. If you are in the United States or Europe, especially in a region with better projects, the information fluency will be much better, and there will be more exchanges among scholars between regions. Although it will not be updated in real time, it will not be much slower.

Especially compared with laboratories in backward areas and countries, this period of difference is very decisive.

If you change to another domestic laboratory, if you find that you have been lagging behind the mainstream international scientific research results for two or a year, will you still participate in such a fierce scientific research competition? Most of you will choose to retreat.

After all, limited funds cannot be wasted.

Also closely related to funding is the time and timing of the publication of the paper.

If we look at the prejudice of the country and region, European laboratories are the most capable laboratories. There are many laboratories that have been sharpening their swords for ten years. Then, Japanese laboratories are more capable. They originally tend to communicate in China, and the independence and authority of scientific researchers can be relatively guaranteed, so it is not too much trouble to hold on for three or five years or even seven or eight years.

In comparison, American laboratories are not that hard to hold back. Sometimes, for the sake of funding, laboratories can’t wait to publish their results.

For example, the relationship between rhodopsin and adrenaline-receptive genes in cattle, if this result is not published, it may be one or two years ahead of other laboratories - of course, it may be one or two months.

This also depends on the laboratory's requirements for results.

If the goal is just to publish a CNS-level paper, then the relationship between the two is enough. If the goal is achieved, it is naturally to publish the paper without hesitation.

But if the goal is a Nobel Prize-level achievement, even if you take risks, you may have to wait for a while before you publish it. The benefits of high funds, wide sources, and low restrictions are usually reflected in this.

In reality, the publication of the relationship between bovine rhodopsin protein and adrenergic receptor genes also represents the study of G protein-coupled receptors, and has entered a new field.

Most laboratories have once again entered the same starting line.

The cruelty of scientific research competition like a meat grinder is nothing more than this. No matter how deep your previous efforts are, as long as there is someone who has already published your results, everyone has to start over.

However, Su Xiankai and others obviously have not felt the cruelty of scientific research competition, especially the cruelty of the world's top scientific research competition.

A few of them looked at the literature talking and laughing, and then threw two little pony tales to Yang Rui as encouragement.

Including Xu Zhengping, the oldest, also looked at the three of them with an optimistic smile. He was not going to participate in this project, but it did not hinder his expectations for the project.

Only when the ion channel laboratory develops well can the teams in the laboratory survive well, which has been proven long ago.

Yang Rui would not hit them even more. He made them happy for a while, and then said: "Now that the goal has been clear, we will follow the direction we have developed with our predecessors. The first step is to extract the ox rhodopsin protein. Who will do it?"

The three of them looked at each other, and Su Xiankai said, "I'll be the striker."

"Then I'll leave it to you. I want a lot of bovine rhodopsin protein, and it must be purified cleanly."

"Leave it to me." Although Su Xiankai was a little stressed, he still agreed. There was no guarantee of this thing 100% and he could only say that he could do his best.

Yang Rui also confirmed the start of the project.

As the project leader, his instructions are enough to reach this point. Su Xiankai needs to consider how to extract the beef rhodopsin protein afterwards.

This is like a siege battle. Yang Rui wants to capture a fortress in the front line. He does not need to describe in detail the tactics of attacking and killing the fortress. It is the responsibility of the front line commander.

Su Xiankai is the current front-line commander, and he doesn't have to charge independently. The selected scientific research dogs in the room are used to charge him. Only when he reaches a difficult point, a key point, or when he really can't catch up in front, Su Xiankai himself will be asked to come forward.

Regarding the work of Fan Zhenlong and Wang Sisheng, Yang Rui thought for a little, and said, "You are here to read the literature with me, and then do a few sets of repeated experiments. Choose a few G proteins to purify them yourself. Gt, Gs, Gi and so on."

Fan Zhenlong and Wang Sisheng opened their mouths, but in the end they could only nod their heads helplessly, put their ambitions in their hearts, and started with practicing basic skills.

Peking University Ion Channel Laboratory is still not a world-class laboratory. It is not only a lack of funds and equipment, but also a lack of scientific research foundations accumulated by the accumulated scientific research is also a problem.

Fan Zhenlong and Wang Sisheng had never done anything like G protein purification before. On this battlefield, they were equivalent to front-line commanders who had never conducted siege battles. Spending valuable funds and time was also a helpless choice.

In fact, Yang Rui himself has never done G protein purification. The complexity of this work has exceeded the scope that master's students or ordinary doctoral students can master. However, Yang Rui has now surpassed the role of front-line commander, and in the position of battle commander, Yang Rui is already experienced.

Even in the meat mincing battle, Yang Rui was not guilty at all.

With a fund of 6 million US dollars, three active magnates with potential for big bulls, and three magnates have not been used for reserves. They are just focusing on resources. Yang Rui feels that he has the opportunity to fight for Taierzhuang.
Chapter completed!